鳥取大学 染色体工学研究センター

研究成果
所属するすべての研究者の論文を紹介

2024年

  • Human artificial chromosome carrying R-spondin1 and IL-22 expression cassettes in rejuvenated MSCs enhances therapeutic efficacy in ulcerative colitis model mice.
    Yayan Wang, Kanako Kazuki, Genki Hichiwa, Masaharu Hiratsuka, Ryohei Ogihara, Satoshi Abe, Haochen Tu, Yanze Li, Xu Gao, Mitsuo Oshimura, Kazuma Tomizuka, Yasuhiro Kazuki
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 182 2024-12-17
    DOI: 10.1016/j.biopha.2024.117751
  • Novel role of zinc-finger protein 518 in heterochromatin formation on α-satellite DNA
    Shinya Ohta, Jun-Ichirou Ohzeki, Nobuko Sato, Hideki Tanizawa, Claire Yik-Lok Chung, Ken-Ichi Noma, Hiroshi Masumoto
    Nucleic Acids Research 2024-12-03
    DOI: 10.1093/nar/gkae1162
  • Microcell-mediated chromosome transfer between non-identical human iPSCs
    Narumi Uno, Hitomaru Miyamoto, Kyotaro Yamazaki, Masaya Egawa, Hiroaki Kobayashi, Kanako Kazuki, Mitsuhiko Osaki, Teruhiko Suzuki, Shusei Hamamichi, Mitsuo Oshimura, Kazuma Tomizuka, Yasuhiro Kazuki
    Molecular Therapy - Nucleic Acids 35(4) 2024-12
    DOI: 10.1016/j.omtn.2024.102382
  • Mice carrying the full-length human immunoglobulin loci produce antigen-specific human antibodies with the lambda light chain
    Kazuto Shimoya, Takashi Moriwaki, Kanako Kazuki, Akane Okada, Shigenori Baba, Yuana Masuda, Satoshi Abe, Yasuhiro Kazuki
    iScience 27(12) 2024-12
    DOI: 10.1016/j.isci.2024.111258
  • Generation of Monosomy 21q Human iPS Cells by CRISPR/Cas9‐Mediated Interstitial Megabase Deletion
    Masaya Egawa, Narumi Uno, Rina Komazaki, Yusuke Ohkame, Kyotaro Yamazaki, Chihiro Yoshimatsu, Yuki Ishizu, Yusaku Okano, Hitomaru Miyamoto, Mitsuhiko Osaki, Teruhiko Suzuki, Kazuyoshi Hosomichi, Yasunori Aizawa, Yasuhiro Kazuki, Kazuma Tomizuka
    Genes to Cells 30(1) 2024-11-24
    DOI: 10.1111/gtc.13184
  • Prevention of liver metastasis via the pharmacological suppression of AMIGO2 expression in tumor cells.
    HeeKyung Seong, Yusuke Kanda, Runa Izutsu, Jumond P Jehung, Junichi Hamada, Mitsuhiko Osaki, Koji Okamoto, Futoshi Okada
    Scientific reports 14(1) 2024-11-15
    DOI: 10.1038/s41598-024-71827-z
  • Structural variation in the pangenome of wild and domesticated barley
    Murukarthick Jayakodi, Qiongxian Lu, Hélène Pidon, M. Timothy Rabanus-Wallace, Micha Bayer, Thomas Lux, Yu Guo, Benjamin Jaegle, Ana Badea, Wubishet Bekele, Gurcharn S. Brar, Katarzyna Braune, Boyke Bunk, Kenneth J. Chalmers, Brett Chapman, Morten Egevang Jørgensen, Jia-Wu Feng, Manuel Feser, Anne Fiebig, Heidrun Gundlach, Wenbin Guo, Georg Haberer, Mats Hansson, Axel Himmelbach, Iris Hoffie, Robert E. Hoffie, Haifei Hu, Sachiko Isobe, Patrick König, Sandip M. Kale, Nadia Kamal, Gabriel Keeble-Gagnère, Beat Keller, Manuela Knauft, Ravi Koppolu, Simon G. Krattinger, Jochen Kumlehn, Peter Langridge, Chengdao Li, Marina P. Marone, Andreas Maurer, Klaus F. X. Mayer, Michael Melzer, Gary J. Muehlbauer, Emiko Murozuka, Sudharsan Padmarasu, Dragan Perovic, Klaus Pillen, Pierre A. Pin, Curtis J. Pozniak, Luke Ramsay, Pai Rosager Pedas, Twan Rutten, Shun Sakuma, Kazuhiro Sato, Danuta Schüler, Thomas Schmutzer, Uwe Scholz, Miriam Schreiber, Kenta Shirasawa, Craig Simpson, Birgitte Skadhauge, Manuel Spannagl, Brian J. Steffenson, Hanne C. Thomsen, Josquin F. Tibbits, Martin Toft Simmelsgaard Nielsen, Corinna Trautewig, Dominique Vequaud, Cynthia Voss, Penghao Wang, Robbie Waugh, Sharon Westcott, Magnus Wohlfahrt Rasmussen, Runxuan Zhang, Xiao-Qi Zhang, Thomas Wicker, Christoph Dockter, Martin Mascher, Nils Stein
    Nature 2024-11-13
    DOI: 10.1038/s41586-024-08187-1
  • The small GTPase RAB-18 is involved in regulating development/diapause by recruiting the intestinal cholesterol transporter NCR-1 onto the apical side in Caenorhabditis elegans
    Toshikuni Awazu, Kanato Sakamoto, Yuka Minagi, Masumi Ohnishi, Tomohiro Bito, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano
    Biochemical and Biophysical Research Communications 734 2024-11
    DOI: 10.1016/j.bbrc.2024.150609
  • Rejuvenation of human mesenchymal stem cells using a nonintegrative and conditionally removable Sendai virus vector.
    Mitsuo Oshimura, Toshiaki Tabata, Narumi Uno, Shuta Takata, Genki Hichiwa, Iori Kanazawa, Takeshi Endo, Kazuhisa Honma, Yayan Wang, Kanako Kazuki, Haochen Tu, Yuichi Iida, Satoshi Abe, Yasuhiro Kazuki
    Scientific reports 14(1) 2024-10-09
    DOI: 10.1038/s41598-024-74757-y
  • AMIGO2 enhances the invasive potential of colorectal cancer by inducing EMT.
    Runa Izutsu, Mitsuhiko Osaki, HeeKyung Seong, Sanami Ogata, Reo Sato, Jun-Ichi Hamada, Futoshi Okada
    Cancer gene therapy 2024-10-08
    DOI: 10.1038/s41417-024-00842-z
  • Developing a workflow for the isolation of hybridoma cells producing fully human antigen-specific antibodies using a surface IgG detection method.
    Hiroyuki Satofuka, Yayan Wang, Hiroshi Tanaka, Kei Hiramatsu, Kayoko Morimoto, Haruka Takayama, Haochen Tu, Yu Qiao, Satoru Ito, Xu Gao, Mitsuo Oshimura, Yasuhiro Kazuki
    Scientific reports 14(1) 2024-10-04
    DOI: 10.1038/s41598-024-73770-5
  • Chemical Diversification of Enzymatically Assembled Polyubiquitin Chains to Decipher the Ubiquitin Codes Programmed on the Branch Structure
    Takafumi Furuhata, Bumkyu Choi, Taiki Uno, Ryota Shinohara, Yusuke Sato, Kei Okatsu, Shuya Fukai, Akimitsu Okamoto
    Journal of the American Chemical Society 2024-10-03
    DOI: 10.1021/jacs.4c11279
  • RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation
    Kazuya Matsuo, Sefan Asamitsu, Kohei Maeda, Hiroyoshi Suzuki, Kosuke Kawakubo, Ginji Komiya, Kenta Kudo, Yusuke Sakai, Karin Hori, Susumu Ikenoshita, Shingo Usuki, Shiori Funahashi, Hideki Oizumi, Atsushi Takeda, Yasushi Kawata, Tomohiro Mizobata, Norifumi Shioda, Yasushi Yabuki
    Cell 2024-10
    DOI: 10.1016/j.cell.2024.09.03710.1101/2023.07.10.548322
  • 分光放射と放射温度を用いたコムギの生長モニタリング
    中尾里菜, 木村玲二, 杉浦李果, 石井孝佳
    沙漠研究 34(3) 2024-10
    DOI: 10.14976/jals.34.3_93
  • Wheat Cybrid Plants, OryzaWheat, Regenerated from Wheat–Rice Hybrid Zygotes via in Vitro Fertilization System Possess Wheat–Rice Hybrid Mitochondria
    Tety Maryenti, Shizuka Koshimizu, Nonoka Onda, Takayoshi Ishii, Kentaro Yano, Takashi Okamoto
    Plant And Cell Physiology 2024-08-07
    DOI: 10.1093/pcp/pcae074
  • Intracerebroventricular 2-hydroxypropyl-γ-cyclodextrin alleviates hepatic manifestations without distributing to the liver in a murine model of Niemann–Pick disease type C
    Yusei Yamada, Yoichi Ishitsuka, Madoka Fukaura-Nishizawa, Tatsuya Kawata, Akira Ishii, Aina Shirakawa, Taichi Sakai, Mayuko Tanaka, Yuki Kondo, Toru Takeo, Naomi Nakagata, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Takahiro Seki, Yuki Kurauchi, Hiroshi Katsuki, Katsumi Higaki, Ryuji Ikeda, Muneaki Matsuo, Takumi Era, Tetsumi Irie
    Life Sciences 350 2024-08
    DOI: 10.1016/j.lfs.2024.122776
  • Centromere sequence-independent but biased loading of subgenome-specific CENH3 variants in allopolyploid Arabidopsis suecica
    Raheleh Karimi-Ashtiyani, Ali Mohammad Banaei-Moghaddam, Takayoshi Ishii, Oda Weiss, Jörg Fuchs, Veit Schubert, Andreas Houben
    Plant Molecular Biology 2024-08
    DOI: 10.1007/s11103-024-01474-5
  • Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation.
    Hiroaki Komatsu, Masayo Okawa, Yasuhiro Kazuki, Kanako Kazuki, Genki Hichiwa, Kazuto Shimoya, Shinya Sato, Fuminori Taniguchi, Mitsuo Oshimura, Tasuku Harada
    Human cell 37(4) 2024-07
    DOI: 10.1007/s13577-024-01064-z
  • Enveloped Viral Replica Equipped with Spike Protein Derived from SARS-CoV-2
    Hiroto Furukawa, Sosuke Nakamura, Ryosuke Mizuta, Kentarou Sakamoto, Hiroshi Inaba, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi, Kazunori Matsuura
    ACS Synthetic Biology 13 2024-06-17
    DOI: 10.1021/acssynbio.4c00165
  • Induction of hepatic CYP3A4 expression by cholesterol and cholic acid: Alterations of gene expression, microsomal activity, and pharmacokinetics.
    Genki Minegishi, Yuka Kobayashi, Mayu Fujikura, Ayane Sano, Yasuhiro Kazuki, Kaoru Kobayashi
    Pharmacology research & perspectives 12(3) 2024-06
    DOI: 10.1002/prp2.1197
  • AMIGO2 is involved in the spread of peritoneal metastasis in serous ovarian cancer via promoting adhesion to the peritoneal mesothelial cells
    Yuki Iida, Mitsuhiko Osaki, Shinya Sato, Runa Izutsu, HeeKyung Seong, Hiroaki Komatsu, Fuminori Taniguchi, Futoshi Okada
    International Journal of Clinical Oncology 29(9) 2024-05-29
    DOI: 10.1007/s10147-024-02556-6
  • The integration of metabolic and proteomic data uncovers an augmentation of the sphingolipid biosynthesis pathway during T-cell differentiation.
    Toshio Kanno, Ryo Konno, Masaru Sato, Atsushi Kurabayashi, Keisuke Miyako, Takahiro Nakajima, Satoru Yokoyama, Shigemi Sasamoto, Hikari K Asou, Junichiro Ohzeki, Yoshinori Hasegawa, Kazutaka Ikeda, Yusuke Kawashima, Osamu Ohara, Yusuke Endo
    Communications biology 7(1) 2024-05-23
    DOI: 10.1038/s42003-024-06339-7
  • Strategy toward In-Cell Self-Assembly of an Artificial Viral Capsid from a Fluorescent Protein-Modified β-Annulus Peptide
    Kentarou Sakamoto, Yuka Yamamoto, Hiroshi Inaba, Kazunori Matsuura
    ACS Synthetic Biology 13 2024-05-10
    DOI: 10.1021/acssynbio.4c00135
  • Genomic analysis of a spontaneous unifoliate mutant reveals gene candidates associated with compound leaf development in Vigna unguiculata [L] Walp
    Offiong Ukpong Edet, Benjamin Ewa Ubi, Takayoshi Ishii
    Scientific Reports 14(1) 2024-05-09
    DOI: 10.1038/s41598-024-61062-x
  • Exosomal miR-493 suppresses MAD2L1 and induces chemoresistance to intraperitoneal paclitaxel therapy in gastric cancer patients with peritoneal metastasis
    Masahiro Makinoya, Kozo Miyatani, Yoshiaki Matsumi, Yu Sakano, Shota Shimizu, Yuji Shishido, Takehiko Hanaki, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Shuichi Takano, Teruhisa Sakamoto, Toshimichi Hasegawa, Hiroaki Saito, Yuji Nakayama, Mitsuhiko Osaki, Futoshi Okada, Yoshiyuki Fujiwara
    Scientific Reports 14(1) 2024-05-02
    DOI: 10.1038/s41598-024-60967-x
  • Alkyl anchor–modified artificial viral capsid budding outside-to-inside and inside-to-outside giant vesicles
    Kazunori Matsuura, Miu Hirahara, Kentarou Sakamoto, Hiroshi Inaba
    Science and Technology of Advanced Materials 25 2024-04-29
    DOI: 10.1080/14686996.2024.2347191
  • 医学用語解説 完全ヒト抗体産生動物を用いたヒト抗体作製
    濱道 修生, 森脇 崇史, 香月 康宏
    炎症と免疫 32(3) 2024-04
  • Mutation of the wheat homeobox gene Grain Number Increase 1 increases grain number and grain yield but decreases grain protein content
    Shun Sakuma, Naho Rokuhara, Shizen Ohnishi, Hironobu Jinno, Yoko Yamashita, Hiroyuki Tanaka
    Euphytica 220(4) 2024-03-28
    DOI: 10.1007/s10681-024-03327-0
  • The hypothetical molecular mechanism of the ethnic variations in the manifestation of age-related macular degeneration; focuses on the functions of the most significant susceptibility genes.
    Shigeru Honda, Norihiko Misawa, Yusuke Sato, Daisuke Oikawa, Fuminori Tokunaga
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2024-03-20
    DOI: 10.1007/s00417-024-06442-9
  • RNA G-quadruplexes and calcium ions synergistically induce Tau phase transitionin vitro
    Yasushi Yabuki, Kazuya Matsuo, Ginji Komiya, Kenta Kudo, Karin Hori, Susumu Ikenoshita, Yasushi Kawata, Tomohiro Mizobata, Norifumi Shioda
    2024-03-03
    DOI: 10.1101/2024.03.01.582861
  • Characterizing ATP processing by the AAA+ protein p97 at the atomic level
    Mikhail Shein, Manuel Hitzenberger, Tat Cheung Cheng, Smruti R. Rout, Kira D. Leitl, Yusuke Sato, Martin Zacharias, Eri Sakata, Anne K. Schütz
    Nature Chemistry 2024-03
    DOI: 10.1038/s41557-024-01440-0
  • Highly genomic instability of super-polyploid strains of Saccharomyces cerevisiae
    Saeka Hirota, Yuji Nakayama, Keisuke Ekino, Satoshi Harashima
    Journal of Bioscience and Bioengineering 137(2) 2024-02
    DOI: 10.1016/j.jbiosc.2023.11.009
  • Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice.
    Yang Li, Yasuhiro Kazuki, Thomas Drabison, Kaoru Kobayashi, Ken-Ichi Fujita, Yue Xu, Yan Jin, Eman Ahmed, Junan Li, Eric D Eisenmann, Sharyn D Baker, Guido Cavaletti, Alex Sparreboom, Shuiying Hu
    Drug metabolism and disposition: the biological fate of chemicals 52(2) 2024-01-09
    DOI: 10.1124/dmd.123.001466
  • Rapid human genomic DNA cloning into mouse artificial chromosome via direct chromosome transfer from human iPSC and CRISPR/Cas9-mediated translocation.
    Hitomaru Miyamoto, Hiroaki Kobayashi, Nanami Kishima, Kyotaro Yamazaki, Shusei Hamamichi, Narumi Uno, Satoshi Abe, Yosuke Hiramuki, Kanako Kazuki, Kazuma Tomizuka, Yasuhiro Kazuki
    Nucleic acids research 52(3) 2024-01-05
    DOI: 10.1093/nar/gkad1218
  • 人類100億人時代到来～作物の細胞を改良して切り拓く未来～
    石井孝佳
    農業および園芸 99(1) 2024-01
年別