鳥取大学 染色体工学研究センター

研究成果
所属するすべての研究者の論文を紹介

2015年

  • Development of a Safeguard System Using an Episomal Mammalian Artificial Chromosome for Gene and Cell Therapy
    Narumi Uno, Katsuhiro Uno, Shinya Komoto, Teruhiko Suzuki, Masaharu Hiratsuka, Mitsuhiko Osaki, Yasuhiro Kazuki, Mitsuo Oshimura
    MOLECULAR THERAPY-NUCLEIC ACIDS 4 2015-12
    DOI: 10.1038/mtna.2015.45
  • Fermented Brown Rice and Rice Bran with Aspergillus oryzae (FBRA) Prevents Inflammation-Related Carcinogenesis in Mice, through Inhibition of Inflammatory Cell Infiltration
    Kunishige Onuma, Yusuke Kanda, Saori Suzuki Ikeda, Ryuta Sakaki, Takuya Nonomura, Masanobu Kobayashi, Mitsuhiko Osaki, Masataka Shikanai, Hiroshi Kobayashi, Futoshi Okada
    NUTRIENTS 7(12) 2015-12
    DOI: 10.3390/nu7125531
  • Preferential recruitment of the maternal centromere-specific histone H3 (CENH3) in oat (Avena sativa L.) x pearl millet (Pennisetum glaucum L.) hybrid embryos
    Takayoshi Ishii, Naohiro Sunamura, Ayaka Matsumoto, Amin Elsadig Eltayeb, Hisashi Tsujimoto
    CHROMOSOME RESEARCH 23(4) 2015-12
    DOI: 10.1007/s10577-015-9477-5
  • CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly
    Nobuaki Shono, Jun-ichirou Ohzeki, Koichiro Otake, Nuno M. C. Martins, Takahiro Nagase, Hiroshi Kimura, Vladimir Larionov, William C. Earnshaw, Hiroshi Masumoto
    JOURNAL OF CELL SCIENCE 128(24) 2015-12
    DOI: 10.1242/jcs.180786
  • Molecular Mechanisms Underlying Urate-Induced Enhancement of Kv1.5 Channel Expression in HL-1 Atrial Myocytes
    Nani Maharani, Ya Kuang Ting, Jidong Cheng, Akira Hasegawa, Yasutaka Kurata, Peili Li, Yuji Nakayama, Haruaki Ninomiya, Nobuhito Ikeda, Kumi Morikawa, Kazuhiro Yamamoto, Naomasa Makita, Takeshi Yamashita, Yasuaki Shirayoshi, Ichiro Hisatome
    CIRCULATION JOURNAL 79(12) 2015-11
    DOI: 10.1253/circj.CJ-15-0416
  • A metal carbonyl-protein needle composite designed for intracellular CO delivery to modulate NF-κB activity.
    Hiroshi Inaba, Nusrat J M Sanghamitra, Kenta Fujita, Takeya Sho, Takahiro Kuchimaru, Susumu Kitagawa, Shinae Kizaka-Kondoh, Takafumi Ueno
    Molecular bioSystems 11(11) 2015-11
    DOI: 10.1039/c5mb00327j
  • Crystal structure of the anion exchanger domain of human erythrocyte band 3
    Takatoshi Arakawa, Takami Kobayashi-Yurugi, Yilmaz Alguel, Hiroko Iwanari, Hinako Hatae, Momi Iwata, Yoshito Abe, Tomoya Hino, Chiyo Ikeda-Suno, Hiroyuki Kuma, Dongchon Kang, Takeshi Murata, Takao Hamakubo, Alexander D. Cameron, Takuya Kobayashi, Naotaka Hamasaki, So Iwata
    SCIENCE 350(6261) 2015-11
    DOI: 10.1126/science.aaa4335
  • Human mesenchymal stem cell-engineered hepatic cell sheets accelerate liver regeneration in mice
    Noriko Itaba, Yoshiaki Matsumi, Kaori Okinaka, An Afida Ashla, Yohei Kono, Mitsuhiko Osaki, Minoru Morimoto, Naoyuki Sugiyama, Kazuo Ohashi, Teruo Okano, Goshi Shiota
    SCIENTIFIC REPORTS 5 2015-11
    DOI: 10.1038/srep16169
  • Collaboration of local governments and experts responding to the increase of the environmental radiation level secondary to the nuclear accident: a unique activity to relieve residents' anxiety.
    H Fujii, T Iimoto, T Tsuzuki, S Iiizumi, S Someya, S Hamamichi, M M Kessler
    Radiation protection dosimetry 167(1-3) 2015-11
    DOI: 10.1093/rpd/ncv281
  • Repression of hTERT transcription by the introduction of chromosome 3 into human oral squamous cell carcinoma.
    Sachiyo Nishio, Takahito Ohira, Naohiro Sunamura, Mitsuo Oshimura, Kazuo Ryoke, Hiroyuki Kugoh
    Biochemical and biophysical research communications 466(4) 2015-10-30
    DOI: 10.1016/j.bbrc.2015.09.119
  • Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis
    Yasuhiro Watanabe, Yasuhiro Kazuki, Kanako Kazuki, Mitsutaka Ebiki, Mami Nakanishi, Kazuomi Nakamura, Miho Yoshida Yamakawa, Hiroyuki Hosokawa, Tetsuya Ohbayashi, Mitsuo Oshimura, Kenji Nakashima
    MOLECULAR THERAPY-NUCLEIC ACIDS 4 2015-10
    DOI: 10.1038/mtna.2015.28
  • Repression of hTERT transcription by the introduction of chromosome 3 into human oral squarnous cell carcinoma
    Sachiyo Nishio, Takahito Ohira, Naohiro Sunamura, Mitsuo Oshimura, Kazuo Ryoke, Hiroyuki Kugoh
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 466(4) 2015-10
    DOI: 10.1016/j.bbrc.2015.09.119
  • TaqSH1-D, wheat ortholog of rice seed shattering gene qSH1, maps to the interval of a rachis fragility QTL on chromosome 3DL of common wheat (Triticum aestivum)
    Mazen Katkout, Shun Sakuma, Kanako Kawaura, Yasunari Ogihara
    GENETIC RESOURCES AND CROP EVOLUTION 62(7) 2015-10
    DOI: 10.1007/s10722-015-0301-z
  • The crystal structure of heme acquisition system A from Yersinia pseudotuberculosis (HasA(ypt)): Roles of the axial ligand Tyr75 and two distal arginines in heme binding
    Masahiro Kanadani, Takehiro Sato, Tomoya Hino, Shingo Nagano, Shin-ichi Ozaki
    JOURNAL OF INORGANIC BIOCHEMISTRY 151 2015-10
    DOI: 10.1016/j.jinorgbio.2015.07.007
  • Structure and mechanism of the mammalian fructose transporter GLUT5
    Norimichi Nomura, Gregory Verdon, Hae Joo Kang, Tatsuro Shimamura, Yayoi Nomura, Yo Sonoda, Saba Abdul Hussien, Aziz Abdul Qureshi, Mathieu Coincon, Yumi Sato, Hitomi Abe, Yoshiko Nakada-Nakura, Tomoya Hino, Takatoshi Arakawa, Osamu Kusano-Arai, Hiroko Iwanari, Takeshi Murata, Takuya Kobayashi, Takao Hamakubo, Michihiro Kasahara, So Iwata, David Drew
    NATURE 526(7573) 2015-10
    DOI: 10.1038/nature14909
  • The Genetic Basis of Composite Spike Form in Barley and 'Miracle-Wheat'
    Naser Poursarebani, Tina Seidensticker, Ravi Koppolu, Corinna Trautewig, Piotr Gawronski, Federica Bini, Geetha Govind, Twan Rutten, Shun Sakuma, Akemi Tagiri, Gizaw M. Wolde, Helmy M. Youssef, Abdulhamit Battal, Stefano Ciannamea, Tiziana Fusca, Thomas Nussbaumer, Carlo Pozzi, Andreas Boerner, Udda Lundqvist, Takao Komatsuda, Silvio Salvi, Roberto Tuberosa, Cristobal Uauy, Nese Sreenivasulu, Laura Rossini, Thorsten Schnurbusch
    GENETICS 201(1) 2015-09
    DOI: 10.1534/genetics.115.176628
  • Point mutation impairs centromeric CENH3 loading and induces haploid plants
    Raheleh Karimi-Ashtiyani, Takayoshi Ishii, Markus Niessen, Nils Stein, Stefan Heckmann, Maia Gurushidze, Ali Mohammad Banaei-Moghaddam, Joerg Fuchs, Veit Schubert, Kerstin Koch, Oda Weiss, Dmitri Demidov, Klaus Schmidt, Jochen Kumlehn, Andreas Houben
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112(36) 2015-09
    DOI: 10.1073/pnas.1504333112
  • Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver
    Kota Kato, Masato Ohbuchi, Satoko Hamamura, Hiroki Ohshita, Yasuhiro Kazuki, Mitsuo Oshimura, Koya Sato, Naoyuki Nakada, Akio Kawamura, Takashi Usui, Hidetaka Kamimura, Chise Tateno
    DRUG METABOLISM AND DISPOSITION 43(8) 2015-08
    DOI: 10.1124/dmd.115.063479
  • Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation
    Yuki Yoshimura, Kazuomi Nakamura, Takeshi Endo, Naoyo Kajitani, Kanako Kazuki, Yasuhiro Kazuki, Hiroyuki Kugoh, Mitsuo Oshimura, Tetsuya Ohbayashi
    TRANSGENIC RESEARCH 24(4) 2015-08
    DOI: 10.1007/s11248-015-9884-6
  • Reactivation of persistent Epstein-Barr virus (EBV) causes secretion of thyrotropin receptor antibodies (TRAbs) in EBV-infected B lymphocytes with TRAbs on their surface
    Keiko Nagata, Yuji Nakayama, Katsumi Higaki, Marika Ochi, Kyosuke Kanai, Michiko Matsushita, Satoshi Kuwamoto, Masako Kato, Ichiro Murakami, Takeshi Iwasaki, Eiji Nanba, Hiroshi Kimura, Kazuhiko Hayashi
    AUTOIMMUNITY 48(5) 2015-08
    DOI: 10.3109/08916934.2015.1022163
  • Apoptosis induced by an uromodulin mutant C112Y and its suppression by topiroxostat
    Sulistiyati Bayu Utami, Endang Mahati, Peili Li, Nani Maharani, Nobuhito Ikeda, Udin Bahrudin, Chishio Munemura, Makoto Hosoyamada, Yasutaka Yamamoto, Akio Yoshida, Yuji Nakayama, Katsumi Higaki, Eiji Nanba, Haruaki Ninomiya, Yasuaki Shirayoshi, Kimiyoshi Ichida, Kazuhiro Yamamoto, Tatsuo Hosoya, Ichiro Hisatome
    CLINICAL AND EXPERIMENTAL NEPHROLOGY 19(4) 2015-08
    DOI: 10.1007/s10157-014-1032-8
  • Evolution of the Grain Dispersal System in Barley.
    Mohammad Pourkheirandish, Goetz Hensel, Benjamin Kilian, Natesan Senthil, Guoxiong Chen, Mohammad Sameri, Perumal Azhaguvel, Shun Sakuma, Sidram Dhanagond, Rajiv Sharma, Martin Mascher, Axel Himmelbach, Sven Gottwald, Sudha K Nair, Akemi Tagiri, Fumiko Yukuhiro, Yoshiaki Nagamura, Hiroyuki Kanamori, Takashi Matsumoto, George Willcox, Christopher P Middleton, Thomas Wicker, Alexander Walther, Robbie Waugh, Geoffrey B Fincher, Nils Stein, Jochen Kumlehn, Kazuhiro Sato, Takao Komatsuda
    Cell 162(3) 2015-07-30
    DOI: 10.1016/j.cell.2015.07.002
  • Cellular uptake and in vivo distribution of polyhistidine peptides
    Takashi Iwasaki, Yoshihisa Tokuda, Ayaka Kotake, Hiroyuki Okada, Shuji Takeda, Tsuyoshi Kawano, Yuji Nakayama
    JOURNAL OF CONTROLLED RELEASE 210 2015-07
    DOI: 10.1016/j.jconrel.2015.05.268
  • Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome
    Masaharu Hiratsuka, Kana Ueda, Narumi Uno, Katsuhiro Uno, Sayaka Fukuhara, Hajime Kurosaki, Shoko Takehara, Mitsuhiko Osaki, Yasuhiro Kazuki, Yoshikazu Kurosawa, Takafumi Nakamura, Motonobu Katoh, Mitsuo Oshimura
    BMC BIOTECHNOLOGY 15 2015-06
    DOI: 10.1186/s12896-015-0142-z
  • The differential loading of two barley CENH3 variants into distinct centromeric substructures is cell type- and development-specific
    Takayoshi Ishii, Raheleh Karimi-Ashtiyani, Ali Mohammad Banaei-Moghaddam, Veit Schubert, Joerg Fuchs, Andreas Houben
    CHROMOSOME RESEARCH 23(2) 2015-06
    DOI: 10.1007/s10577-015-9466-8
  • Structure of Slitrk2-PTPδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion.
    Atsushi Yamagata, Yusuke Sato, Sakurako Goto-Ito, Takeshi Uemura, Asami Maeda, Tomoko Shiroshima, Tomoyuki Yoshida, Shuya Fukai
    Scientific reports 5 2015-05-19
    DOI: 10.1038/srep09686
  • Stable complex formation of CENP-B with the CENP-A nucleosome
    Risa Fujita, Koichiro Otake, Yasuhiro Arimura, Naoki Horikoshi, Yuta Miya, Tatsuya Shiga, Akihisa Osakabe, Hiroaki Tachiwana, Jun-ichirou Ohzeki, Vladimir Larionov, Hiroshi Masumoto, Hitoshi Kurumizaka
    NUCLEIC ACIDS RESEARCH 43(10) 2015-05
    DOI: 10.1093/nar/gkv405
  • Decreased pulmonary function in school children in Western Japan after exposures to Asian desert dusts and its association with interleukin-8.
    Watanabe M, Hisashi Noma, Kurai J, Sano H, Saito R, Satoshi Abe, Yutaka Kimura, Aiba S, Oshimura M, Yamasaki A, Shimizu E
    BioMed research international 2015-04-28
    DOI: 10.1155/2015/583293
  • Mechanisms of splicing-dependent trans-synaptic adhesion by PTPδ-IL1RAPL1/IL-1RAcP for synaptic differentiation.
    Atsushi Yamagata, Tomoyuki Yoshida, Yusuke Sato, Sakurako Goto-Ito, Takeshi Uemura, Asami Maeda, Tomoko Shiroshima, Shiho Iwasawa-Okamoto, Hisashi Mori, Masayoshi Mishina, Shuya Fukai
    Nature communications 6 2015-04-24
    DOI: 10.1038/ncomms7926
  • Comparison of genome-wide gene expression patterns in the seedlings of nascent allohexaploid wheats produced by two combinations of hybrids
    Yeonju Jung, Kanako Kawaura, Masahiro Kishii, Shun Sakuma, Yasunari Ogihara
    GENES & GENETIC SYSTEMS 90(2) 2015-04
    DOI: 10.1266/ggs.90.79
  • Crystal structures of the human adiponectin receptors
    Hiroaki Tanabe, Yoshifumi Fujii, Miki Okada-Iwabu, Masato Iwabu, Yoshihiro Nakamura, Toshiaki Hosaka, Kanna Motoyama, Mariko Ikeda, Motoaki Wakiyama, Takaho Terada, Noboru Ohsawa, Masakatsu Hato, Satoshi Ogasawara, Tomoya Hino, Takeshi Murata, So Iwata, Kunio Hirata, Yoshiaki Kawano, Masaki Yamamoto, Tomomi Kimura-Someya, Mikako Shirouzu, Toshimasa Yamauchi, Takashi Kadowaki, Shigeyuki Yokoyama
    NATURE 520(7547) 2015-04
    DOI: 10.1038/nature14301
  • Cystathionine Is a Novel Substrate of Cystine/Glutamate Transporter IMPLICATIONS FOR IMMUNE FUNCTION
    Sho Kobayashi, Mami Sato, Takayuki Kasakoshi, Takumi Tsutsui, Masahiro Sugimoto, Mitsuhiko Osaki, Futoshi Okada, Kiharu Igarashi, Jun Hiratake, Takujiro Homma, Marcus Conrad, Junichi Fujii, Tomoyoshi Soga, Shiro Bannai, Hideyo Sato
    JOURNAL OF BIOLOGICAL CHEMISTRY 290(14) 2015-04
    DOI: 10.1074/jbc.M114.625053
  • MiRNA therapy targeting cancer stem cells: A new paradigm for cancer treatment and prevention of tumor recurrence
    Mitsuhiko Osaki, Futoshi Okada, Takahiro Ochiya
    Therapeutic Delivery 6(3) 2015-04-01
    DOI: 10.4155/tde.14.122
  • Construction of a Luciferase Reporter System to Monitor Osteogenic Differentiation of Mesenchymal Stem Cells by Using a Mammalian Artificial Chromosome Vector
    Takashi Narai, Motonobu Katoh, Toshiaki Inoue, Makoto Taniguchi, Kanako Kazuki, Yasuhiro Kazuki, Kenzo Sato, Isamu Kodani, Kazuo Ryoke, Mitsuo Oshimura
    YONAGO ACTA MEDICA 58(1) 2015-03
  • Structures of CYLD USP with Met1-or Lys63-linked diubiquitin reveal mechanisms for dual specificity
    Yusuke Sato, Eiji Goto, Yuri Shibata, Yuji Kubota, Atsushi Yamagata, Sakurako Goto-Ito, Keiko Kubota, Jun-ichiro Inoue, Mutsuhiro Takekawa, Fuminori Tokunaga, Shuya Fukai
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 22(3) 2015-03
    DOI: 10.1038/nsmb.2970
  • Structural Basis for Ubiquitin Recognition by Ubiquitin-Binding Zinc Finger of FAAP20
    Aya Toma, Tomio S. Takahashi, Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Shinichiro Nakada, Atsuhiko Fukuto, Yasunori Horikoshi, Satoshi Tashiro, Shuya Fukai
    PLOS ONE 10(3) 2015-03
    DOI: 10.1371/journal.pone.0120887
  • Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2
    Hiroaki Tanabe, Kanna Motoyama, Mariko Ikeda, Motoaki Wakiyama, Takaho Terada, Noboru Ohsawa, Toshiaki Hosaka, Masakatsu Hato, Yoshifumi Fujii, Yoshihiro Nakamura, Satoshi Ogasawara, Tomoya Hino, Takeshi Murata, So Iwata, Miki Okada-Iwabu, Masato Iwabu, Kunio Hirata, Yoshiaki Kawano, Masaki Yamamoto, Tomomi Kimura-Someya, Mikako Shirouzu, Toshimasa Yamauchi, Takashi Kadowaki, Shigeyuki Yokoyama
    Journal of Structural and Functional Genomics 16(1) 2015-03
    DOI: 10.1007/s10969-014-9192-z
  • A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges
    Mitsuo Oshimura, Narumi Uno, Yasuhiro Kazuki, Motonobu Katoh, Toshiaki Inoue
    CHROMOSOME RESEARCH 23(1) 2015-02
    DOI: 10.1007/s10577-014-9459-z
  • miR-19b regulates hTERT mRNA expression through targeting PITX1 mRNA in melanoma cells
    Takahito Ohira, Sunamura Naohiro, Yuji Nakayama, Mitsuhiko Osaki, Futoshi Okada, Mitsuo Oshimura, Hiroyuki Kugoh
    SCIENTIFIC REPORTS 5 2015-02
    DOI: 10.1038/srep08201
  • Genetic and epigenetic regulation of centromeres: a look at HAC formation
    Jun-ichirou Ohzeki, Vladimir Larionov, William C. Earnshaw, Hiroshi Masumoto
    CHROMOSOME RESEARCH 23(1) 2015-02
    DOI: 10.1007/s10577-015-9470-z
  • Recurrent Micronucleation through Cell Cycle Progression in the Presence of Microtubule Inhibitors
    Yuji Nakayama, Narumi Uno, Katsuhiro Uno, Yamato Mizoguchi, Shinya Komoto, Yasuhiro Kazuki, Eiji Nanba, Toshiaki Inoue, Mitsuo Oshimura
    CELL STRUCTURE AND FUNCTION 40(1) 2015
    DOI: 10.1247/csf.14005
  • Protein Needles as Molecular Templates for Artificial Metalloenzymes
    Hiroshi Inaba, Susumu Kitagawa, Takafumi Ueno
    ISRAEL JOURNAL OF CHEMISTRY 55(1) 2015-01
    DOI: 10.1002/ijch.201400097
  • Design of biomaterials for intracellular delivery of carbon monoxide
    Hiroshi Inaba, Kenta Fujita, Takafumi Ueno
    BIOMATERIALS SCIENCE 3(11) 2015
    DOI: 10.1039/c5bm00210a
  • Potent chemical chaperone compounds for GM1-gangliosidosis: N-substituted (+)-conduramine F-4 derivatives.
    Kuno S, Higaki K, Takahashi A, Nanba E, Ogawa S
    MedChemComm 6 2015
  • Conformationally –locked N-glycosidase: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease.
    Castilla J, Risquez R, Higaki K, Nanba E, Ohno K, Suzuki Y, Diaz Y, Ortiz Mellet C, Garcia Fernandez JM, Castillion S
    Eur J Med Chem. 90 2015
  • Highly pH-responsive pharmacological chaperones for mutant glycosidase enhancement.
    Mena-Barragán T, Narita A, Matias D, Tiscornia G, Nanba E, Ohno K, Suzuki Y, Higaki K, García Fernández JM, Ortiz Mellet C
    Angew Chem Int Ed Engl 54 2015
  • Inhibitor of apoptosis proteins (IAPs) may be effective therapeutic targets for treating endometriosis
    Takashi Uegaki, Fuminori Taniguchi, Kazuomi Nakamura, Mitsuhiko Osaki, Futoshi Okada, Osamu Yamamoto, Tasuku Harada
    HUMAN REPRODUCTION 30(1) 2015-01
    DOI: 10.1093/humrep/deu288
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