鳥取大学 染色体工学研究センター

研究成果
所属するすべての研究者の論文を紹介

2022年

  • Characterization of proteogenomic signatures of differentiation of CD4 + T cell subsets.
    Toshio Kanno, Ryo Konno, Keisuke Miyako, Takahiro Nakajima, Satoru Yokoyama, Shigemi Sasamoto, Hikari K Asou, Junichiro Ohzeki, Yusuke Kawashima, Yoshinori Hasegawa, Osamu Ohara, Yusuke Endo
    DNA research : an international journal for rapid publication of reports on genes and genomes 30(1) 2022-12-29
    DOI: 10.1093/dnares/dsac054
  • Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery.
    Kyotaro Yamazaki, Kyosuke Matsuo, Akane Okada, Narumi Uno, Teruhiko Suzuki, Satoshi Abe, Shusei Hamamichi, Nanami Kishima, Shota Togai, Kazuma Tomizuka, Yasuhiro Kazuki
    Scientific reports 12(1) 2022-12-16
    DOI: 10.1038/s41598-022-25959-9
  • Spinocerebellar ataxia type 17-digenic TBP/STUB1 disease: neuropathologic features of an autopsied patient
    Rie Saito, Yui Tada, Daisuke Oikawa, Yusuke Sato, Makiko Seto, Akira Satoh, Kodai Kume, Nozomi Ueki, Masahiro Nakashima, Shintaro Hayashi, Yasuko Toyoshima, Fuminori Tokunaga, Hideshi Kawakami, Akiyoshi Kakita
    Acta Neuropathologica Communications 10(1) 2022-12-07
    DOI: 10.1186/s40478-022-01486-6
  • Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans-chromosomic mouse line expressing human UGT2 enzymes.
    Kaoru Kobayashi, Tsuneo Deguchi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Kazuomi Nakamura, Atsushi Kurihara, Mitsuo Oshimura, Yasuhiro Kazuki
    Pharmacology research & perspectives 10(6) 2022-12
    DOI: 10.1002/prp2.1030
  • Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci
    Hiroyuki Satofuka, Satoshi Abe, Takashi Moriwaki, Akane Okada, Kanako Kazuki, Hiroshi Tanaka, Kyotaro Yamazaki, Genki Hichiwa, Kayoko Morimoto, Haruka Takayama, Yuji Nakayama, Shinya Hatano, Yutaro Yada, Yasufumi Murakami, Yoshihiro Baba, Mitsuo Oshimura, Kazuma Tomizuka, Yasuhiro Kazuki
    Nature Communications 13(1) 2022-12
    DOI: 10.1038/s41467-022-29421-2
  • GPX4 Regulates Tumor Cell Proliferation via Suppressing Ferroptosis and Exhibits Prognostic Significance in Gastric Cancer.
    Ken Sugezawa, Masaki Morimoto, Manabu Yamamoto, Yoshiaki Matsumi, Yuji Nakayama, Kazushi Hara, Chihiro Uejima, Kyoichi Kihara, Tomoyuki Matsunaga, Naruo Tokuyasu, Teruhisa Sakamoto, Yoshihisa Umekita, Yoshiyuki Fujiwara
    Anticancer research 42(12) 2022-12
    DOI: 10.21873/anticanres.16079
  • The impact of AMIGO2 on prognosis and hepatic metastasis in gastric cancer patients
    Keisuke Goto, Masaki Morimoto, Mitsuhiko Osaki, Akimitsu Tanio, Runa Izutsu, Yoshiyuki Fujiwara, Futoshi Okada
    BMC Cancer 22(1) 2022-12
    DOI: 10.1186/s12885-022-09339-0
  • Metabolic disposition of triazolam and clobazam in humanized CYP3A mice with a double knockout background of mouse Cyp2c and Cyp3a genes.
    Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki, Yasuhiro Kazuki
    Drug metabolism and disposition: the biological fate of chemicals 2022-11-15
    DOI: 10.1124/dmd.122.001087
  • Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes.
    Kobayashi K, Minegishi G, Kuriyama N, Miyajima A, Abe S, Kazuki K, Kazuki Y
    Drug metabolism and disposition: the biological fate of chemicals 2022-11-15
    DOI: 10.1124/dmd.122.001087
  • Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann–Pick disease type C without hearing loss
    Yusei Yamada, Toru Miwa, Masaki Nakashima, Aina Shirakawa, Akira Ishii, Nanami Namba, Yuki Kondo, Toru Takeo, Naomi Nakagata, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Yuki Kurauchi, Takahiro Seki, Hiroshi Katsuki, Yasuyo Okada, Atsushi Ichikawa, Katsumi Higaki, Ken Hayashi, Kentaro Minami, Naoki Yoshikawa, Ryuji Ikeda, Yoshihide Ishikawa, Tomohito Kajii, Kyoko Tachii, Hiroki Takeda, Yorihisa Orita, Muneaki Matsuo, Tetsumi Irie, Yoichi Ishitsuka
    Biomedicine & Pharmacotherapy 155 2022-11
    DOI: 10.1016/j.biopha.2022.113698
  • Effects of 6-O-α-maltosyl-β cyclodextrin on lipid metabolism in Npc1-deficient Chinese hamster ovary cells.
    By Yasuyo Okada, Sayako Kuroiwa, Ayaka Noi, Ayaka Tanaka, Junichi Nishikawa, Yuki Kondo, Yoichi Ishitsuka, Tetsumi Irie, Katsumi Higaki, Muneaki Matsuo, Atsushi Ichikawa
    Molecular genetics and metabolism 137(3) 2022-11
    DOI: 10.1016/j.ymgme.2022.09.007
  • The FMRFamide-like peptide FLP-1 modulates larval development by regulating the production and secretion of the insulin-like peptide DAF-28 in Caenorhabditis elegans
    Risako Une, Natsumi Kageyama, Masahiro Ono, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano
    Bioscience, Biotechnology, and Biochemistry in press 2022-11
  • Kidney organoid derived from renal tissue stem cells is a useful tool for histopathological assessment of nephrotoxicity in a cisplatin-induced acute renal tubular injury model.
    Shota Ueno, Kenji Kokura, Yasushi Kuromi, Mitsuhiko Osaki, Futoshi Okada, Shinji Kitamura, Tetsuya Ohbayashi
    Journal of toxicologic pathology 35(4) 2022-10
    DOI: 10.1293/tox.2022-0006
  • Identification and molecular analysis of RNF31 Q622H germline polymorphism
    Seshiru Nakazawa, Ryo Mamiya, Reika Kawabata‑Iwakawa, Daisuke Oikawa, Kyoichi Kaira, Fuminori Tokunaga, Sumihito Nobusawa, Yusuke Sato, Atsushi Sasaki, Toshiki Yajima, Ken Shirabe
    Oncology Letters 24(5) 2022-09-21
    DOI: 10.3892/ol.2022.13514
  • マウス人工染色体ベクターを用いたHLA-A,B,C遺伝子領域保持マウスの作製と解析
    岸間 菜々美, 森脇 崇史, 香月 加奈子, 中川 和奏, 宇野 愛海, 冨塚 一磨, 鈴木 輝彦, 香月 康宏
    MHC: Major Histocompatibility Complex 29(2Suppl.) 2022-09
  • センダイウイルスを用いた正常卵巣およびBRCA-1/-2変異のある患者卵巣表層上皮不死化細胞株樹立と解析(Establishment of Sendai virus-mediated reversibly immortalized ovarian cell lines from normal and BRCA-1/2 mutation)
    小松 宏彰, 香月 康宏, 香月 加奈子, 大川 雅世, 曳野 耕平, 飯田 祐基, 澤田 真由美, 細川 雅代, 工藤 明子, 千酌 潤, 佐藤 慎也, 谷口 文紀
    日本癌学会総会記事 81回 2022-09
  • Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism
    Shotaro Uehara, Yuichi Iida, Miyuki Ida-Tanaka, Motohito Goto, Kenji Kawai, Masafumi Yamamoto, Yuichiro Higuchi, Satoshi Ito, Riichi Takahashi, Hidetaka Kamimura, Mamoru Ito, Hiroshi Yamazaki, Mitsuo Oshimura, Yasuhiro Kazuki, Hiroshi Suemizu
    Scientific Reports 12(1) 2022-09-01
    DOI: 10.1038/s41598-022-19242-0
  • Stabilization of Artificial Viral Capsid Using Surface Modification with BODIPY
    Kazunori Matsuura, Satomi Yano, Haruka Ohtani, Risako Kobayashi, Hiroshi Inaba
    Chemistry Letters 51(11) 2022-09
    DOI: 10.1246/cl.220398
  • Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside
    Hiroshi Inaba, Yurina Sueki, Muneyoshi Ichikawa, Arif Md. Rashedul Kabir, Takashi Iwasaki, Hideki Shigematsu, Akira Kakugo, Kazuki Sada, Tomoya Tsukazaki, Kazunori Matsuura
    Science Advances 8(36) 2022-09
    DOI: 10.1126/sciadv.abq3817
  • Structural insights into the G protein selectivity revealed by the human EP3-Gi signaling complex
    Ryoji Suno, Yukihiko Sugita, Kazushi Morimoto, Hiroko Takazaki, Hirokazu Tsujimoto, Mika Hirose, Chiyo Suno-Ikeda, Norimichi Nomura, Tomoya Hino, Asuka Inoue, Kenji Iwasaki, Takayuki Kato, So Iwata, Takuya Kobayashi
    Cell Reports 40(11) 2022-09
    DOI: 10.1016/j.celrep.2022.111323
  • 雑種胚細胞で起こる染色体脱落の理解と育種的利用
    石井孝佳
    育種学研究 2022-09
    DOI: 10.1270/jsbbr.22j11
  • Mechanistic Studies for the Rational Design of Multivalent Glycodendrimers
    Yoshiyuki Manabe, Masato Tsutsui, Kohtaro Hirao, Risako Kobayashi, Hiroshi Inaba, Kazunori Matsuura, Daisuke Yoshidome, Kazuya Kabayama, Koichi Fukase
    Chemistry – A European Journal 28(61) 2022-08-31
    DOI: 10.1002/chem.202201848
  • Cowpea speed breeding using regulated growth chamber conditions and seeds of oven-dried immature pods potentially accommodates eight generations per year
    Offiong Ukpong Edet, Takayoshi Ishii
    Plant Methods 18(1) 2022-08-29
    DOI: 10.1186/s13007-022-00938-3
  • Influence of MDR1 gene polymorphism (2677G>T) on expression and function of P-glycoprotein at the blood-brain barrier: utilizing novel P-glycoprotein humanized mice with mutation.
    Yuki Yamasaki, Takashi Moriwaki, Seiryo Ogata, Shingo Ito, Sumio Ohtsuki, Genki Minegishi, Satoshi Abe, Yumi Ohta, Kanako Kazuki, Kaoru Kobayashi, Yasuhiro Kazuki
    Pharmacogenetics and genomics 32(8) 2022-08-22
    DOI: 10.1097/FPC.0000000000000481
  • Light-induced stabilization of microtubules by photo-crosslinking of a Tau-derived peptide
    Soei Watari, Hiroshi Inaba, Tomonori Tamura, Arif Md. Rashedul Kabir, Akira Kakugo, Kazuki Sada, Itaru Hamachi, Kazunori Matsuura
    Chemical Communications 58(66) 2022-08
    DOI: 10.1039/d2cc01890j
  • Systemic RNA Interference Defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans.
    Anthony L Gaeta, J Brucker Nourse Jr, Karolina Willicott, Luke E McKay, Candice M Keogh, Kylie Peter, Shannon N Russell, Shusei Hamamichi, Laura A Berkowitz, Kim A Caldwell, Guy A Caldwell
    PLoS genetics 18(8) 2022-08
    DOI: 10.1371/journal.pgen.1010115
  • The FMRFamide-like peptide FLP-2 is involved in the modulation of larval development and adult lifespan by regulating the secretion of the insulin-like peptide INS-35 in Caenorhabditis elegans
    Natsumi Kageyama, Masayo Nose, Masahiro Ono, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano
    Bioscience, Biotechnology, and Biochemistry 86(9) 2022-08
    DOI: 10.1093/bbb/zbac108
  • Liver Metastasis Formation Is Defined by AMIGO2 Expression via Adhesion to Hepatic Endothelial Cells in Human Gastric and Colorectal Cancer Cells.
    Runa Izutsu, Mitsuhiko Osaki, Jumond P Jehung, Hee Kyung Seong, Futoshi Okada
    Pathology, research and practice 237 2022-07-08
    DOI: 10.1016/j.prp.2022.154015
  • Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes.
    Peili Li, Yasutaka Kurata, Fikri Taufiq, Masanari Kuwabara, Haruaki Ninomiya, Katsumi Higaki, Motokazu Tsuneto, Yasuaki Shirayoshi, Miguel A Lanaspa, Ichiro Hisatome
    Molecular biology reports 49(7) 2022-07
    DOI: 10.1007/s11033-022-07378-1
  • Anticancer Activity of Reconstituted Ribonuclease S‐Decorated Artificial Viral Capsid
    Yingbing Liang, Hiroto Furukawa, Kentarou Sakamoto, Hiroshi Inaba, Kazunori Matsuura
    ChemBioChem 23(15) 2022-06-21
    DOI: 10.1002/cbic.202200220
  • Intracellular delivery and photothermal therapeutic effects of polyhistidine peptide-modified gold nanoparticles
    Kosuke Hori, Shinichi Higashida, Tomohiro Osaki, Tsuyoshi Kawano, Hiroshi Inaba, Kazunori Matsuura, Takashi Iwasaki
    Journal of Biotechnology 354 2022-06
    DOI: 10.1016/j.jbiotec.2022.06.006
  • Structural Basis for the Prenylation Reaction of Carbazole‐Containing Natural Products Catalyzed by Squalene Synthase‐Like Enzymes
    Ryuhei Nagata, Hironori Suemune, Masaya Kobayashi, Tetsuro Shinada, Kazuo Shin‐ya, Makoto Nishiyama, Tomoya Hino, Yusuke Sato, Tomohisa Kuzuyama, Shingo Nagano
    Angewandte Chemie International Edition 61(20) 2022-05-09
    DOI: 10.1002/anie.202117430
  • Structural basis for the linkage specificity of ubiquitin-binding domain and deubiquitinase
    Yusuke Sato
    The Journal of Biochemistry 172(1) 2022-04-08
    DOI: 10.1093/jb/mvac031
  • Structural Changes of Microtubules by Encapsulation of Gold Nanoparticles Using a Tau-derived Peptide
    Hiroshi Inaba, Arif Md. Rashedul Kabir, Akira Kakugo, Kazuki Sada, Kazunori Matsuura
    Chemistry Letters 51(4) 2022-04-05
    DOI: 10.1246/cl.210761
  • Combination of CENP-B box positive and negative synthetic alpha satellite repeats improves de novo human artificial chromosome formation.
    Okazaki K, Nakano M, Ohzeki J, Otake K, Kugo K, Larionov V, Earnshaw WC, Masumoto H
    cells 11(9) 2022-04
    DOI: 10.3390/cells11091378
  • Crystal structure of the adenylation domain from an ε-poly-l-lysine synthetase provides molecular mechanism for substrate specificity.
    Takaki Okamoto, Kazuya Yamanaka, Yoshimitsu Hamano, Shingo Nagano, Tomoya Hino
    Biochemical and biophysical research communications 596 2022-03-12
    DOI: 10.1016/j.bbrc.2022.01.053
  • In vitro transcytosis of Helicobacter pylori histidine-rich protein through gastric epithelial-like cells and the blood–brain barrier
    Takashi Iwasaki, Aiki Maruyama, Yurika Inui, Toshihiko Sakurai, Tsuyoshi Kawano
    Bioscience, Biotechnology, and Biochemistry 86(3) 2022-02-24
    DOI: 10.1093/bbb/zbab221
  • Panel of human cell lines with human/mouse artificial chromosomes.
    Narumi Uno, Shuta Takata, Shinya Komoto, Hitomaru Miyamoto, Yuji Nakayama, Mitsuhiko Osaki, Ryota Mayuzumi, Natsumi Miyazaki, Chiaki Hando, Satoshi Abe, Tetsushi Sakuma, Takashi Yamamoto, Teruhiko Suzuki, Yoshihiro Nakajima, Mitsuo Oshimura, Kazuma Tomizuka, Yasuhiro Kazuki
    Scientific reports 12(1) 2022-02-22
    DOI: 10.1038/s41598-022-06814-3
  • A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features.
    Yasuhiro Kazuki, Feng J Gao, Miho Yamakawa, Masumi Hirabayashi, Kanako Kazuki, Naoyo Kajitani, Sachiko Miyagawa-Tomita, Satoshi Abe, Makoto Sanbo, Hiromasa Hara, Hiroshi Kuniishi, Satoshi Ichisaka, Yoshio Hata, Moeka Koshima, Haruka Takayama, Shoko Takehara, Yuji Nakayama, Masaharu Hiratsuka, Yuichi Iida, Satoko Matsukura, Naohiro Noda, Yicong Li, Anna J Moyer, Bei Cheng, Nandini Singh, Joan T Richtsmeier, Mitsuo Oshimura, Roger H Reeves
    American journal of human genetics 109(2) 2022-02-03
    DOI: 10.1016/j.ajhg.2021.12.015
  • An improved TK-NOG mouse as a novel platform for humanized liver that overcomes limitations in both male and female animals
    Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Kenji Kawai, Masafumi Yamamoto, Hidetaka Kamimura, Yuichi Iida, Mitsuo Oshimura, Yasuhiro Kazuki, Hiroshi Yamazaki, Hayato Hikita, Tetsuo Takehara, Hiroshi Suemizu
    Drug Metabolism and Pharmacokinetics 42 2022-02
    DOI: 10.1016/j.dmpk.2021.100410
  • Crystal structures of a 6-dimethylallyltryptophan synthase, IptA: Insights into substrate tolerance and enhancement of prenyltransferase activity
    Hironori Suemune, Doukan Nishimura, Kenjiro Mizutani, Yusuke Sato, Tomoya Hino, Hiroshi Takagi, Yumi Shiozaki-Sato, Shunji Takahashi, Shingo Nagano
    Biochemical and Biophysical Research Communications 593 2022-02
    DOI: 10.1016/j.bbrc.2022.01.018
  • Introduction of a long synthetic repetitive DNA sequence into cultured tobacco cells
    Junichirou Ohzeki, Kazuto Kugou, Koichiro Otake, Koei Okazaki, Seiji Takahashi, Daisuke Shibata, Hiroshi Masumoto
    Plant Biotechnology 39(2) 2022-02
    DOI: 10.5511/plantbiotechnology.21.1210a
  • Activation of PPARγ in bladder cancer via introduction of the long arm of human chromosome 9
    Ryutaro Shimizu, Takahito Ohira, Takuki Yagyu, Tetsuya Yumioka, Noriya Yamaguchi, Hideto Iwamoto, Shuichi Morizane, Katsuya Hikita, Masashi Honda, Atsushi Takenaka, Hiroyuki Kugoh
    Oncology Letters 23(3) 2022-01-27
    DOI: 10.3892/ol.2022.13212
  • AMIGO2 contained in cancer cell-derived extracellular vesicles enhances the adhesion of liver endothelial cells to cancer cells.
    Runa Izutsu, Mitsuhiko Osaki, Hideyuki Nemoto, Maho Jingu, Ryo Sasaki, Yusuke Yoshioka, Takahiro Ochiya, Futoshi Okada
    Scientific reports 12(1) 2022-01-17
    DOI: 10.1038/s41598-021-04662-1
  • MTA1, a metastasis‑associated protein, in endothelial cells is an essential molecule for angiogenesis.
    Mizuho Ishikawa, Mitsuhiko Osaki, Narumi Uno, Takahito Ohira, Hiroyuki Kugoh, Futoshi Okada
    Molecular medicine reports 25(1) 2022-01
    DOI: 10.3892/mmr.2021.12527
  • Embedding a membrane protein into an enveloped artificial viral replica
    Hiroto Furukawa, Hiroshi Inaba, Yoshihiro Sasaki, Kazunari Akiyoshi, Kazunori Matsuura
    RSC Chemical Biology 3(2) 2022
    DOI: 10.1039/d1cb00166c
  • Editorial: Genomics and disease resistance in wheat and maize.
    Cheng Liu, Handong Su, Shun Sakuma, Mingliang Xu, James A Birchler, Fangpu Han
    Frontiers in plant science 13 2022
    DOI: 10.3389/fpls.2022.1064948
  • Diverse reactions catalyzed by cytochrome P450 and biosynthesis of steroid hormone.
    Keisuke Fujiyama, Tomoya Hino, Shingo Nagano
    Biophysics and physicobiology 19 2022
    DOI: 10.2142/biophysico.bppb-v19.0021
  • Prevention of tumor progression in inflammation-related carcinogenesis by anti-inflammatory and anti-mutagenic effects brought about by ingesting fermented brown rice and rice bran with Aspergillus oryzae (FBRA)
    Hideyuki Nemoto, Marina Otake, Takahiro Matsumoto, Runa Izutsu, Jumond P. Jehung, Keisuke Goto, Mitsuhiko Osaki, Masafumi Mayama, Masataka Shikanai, Hiroshi Kobayashi, Tetsushi Watanabe, Futoshi Okada
    Journal of Functional Foods 88 2022-01
    DOI: 10.1016/j.jff.2021.104907
年別