鳥取大学 染色体工学研究センター

研究成果
所属するすべての研究者の論文を紹介

2011年

  • Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
    Sebastian Treusch, Shusei Hamamichi, Jessica L Goodman, Kent E S Matlack, Chee Yeun Chung, Valeriya Baru, Joshua M Shulman, Antonio Parrado, Brooke J Bevis, Julie S Valastyan, Haesun Han, Malin Lindhagen-Persson, Eric M Reiman, Denis A Evans, David A Bennett, Anders Olofsson, Philip L DeJager, Rudolph E Tanzi, Kim A Caldwell, Guy A Caldwell, Susan Lindquist
    Science (New York, N.Y.) 334(6060) 2011-12-02
    DOI: 10.1126/science.1213210
  • [Toward gene and cell therapy using human artificial chromosome].
    Kazuki Y, Oshimura M
    Nihon rinsho. Japanese journal of clinical medicine 69(12) 2011-12
  • Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
    Yusuke Sato, Hiroaki Fujita, Azusa Yoshikawa, Masami Yamashita, Atsushi Yamagata, Stephen E. Kaiser, Kazuhiro Iwai, Shuya Fukai
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108(51) 2011-12
    DOI: 10.1073/pnas.1109088108
  • A new chromosome 14-based human artificial chromosome (HAC) vector system for efficient transgene expression in human primary cells
    Minoru Kakeda, Keiko Nagata, Kanako Osawa, Hiroki Matsuno, Masaharu Hiratsuka, Akiko Sano, Akiyo Okazaki, Shingo Shitara, Satoshi Nishikawa, Anri Masuya, Toshihiro Hata, Shun Wako, Mitsuhiko Osaki, Yasuhiro Kazuki, Mitsuo Oshimura, Kazuma Tomizuka
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 415(3) 2011-11
    DOI: 10.1016/j.bbrc.2011.10.088
  • Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models.
    Zhaohui Liu, Shusei Hamamichi, Byoung Dae Lee, Dejun Yang, Arpita Ray, Guy A Caldwell, Kim A Caldwell, Ted M Dawson, Wanli W Smith, Valina L Dawson
    Human molecular genetics 20(20) 2011-10-15
    DOI: 10.1093/hmg/ddr312
  • Integration-free and stable expression of FVIII using a human artificial chromosome
    Hajime Kurosaki, Masaharu Hiratsuka, Natsuko Imaoka, Yuichi Iida, Narumi Uno, Yasuhiro Kazuki, Chie Ishihara, Yuwna Yakura, Jun Mimuro, Youichi Sakata, Hiroyuki Takeya, Mitsuo Oshimura
    JOURNAL OF HUMAN GENETICS 56(10) 2011-10
    DOI: 10.1038/jhg.2011.88
  • Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors
    Masaharu Hiratsuka, Narumi Uno, Kana Ueda, Hajime Kurosaki, Natsuko Imaoka, Kanako Kazuki, Etsuya Ueno, Yutaro Akakura, Motonobu Katoh, Mitsuhiko Osaki, Yasuhiro Kazuki, Masato Nakagawa, Shinya Yamanaka, Mitsuo Oshimura
    PLOS ONE 6(10) 2011-10
    DOI: 10.1371/journal.pone.0025961
  • Probing the Functional Mechanism of Escherichia coli GroEL Using Circular Permutation
    Tomohiro Mizobata, Tatsuya Uemura, Kazuhiro Isaji, Takuma Hirayama, Kunihiro Hongo, Yasushi Kawata
    PLOS ONE 6(10) 2011-10
    DOI: 10.1371/journal.pone.0026462
  • Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models
    Yasuhiro Kazuki, Mitsuo Oshimura
    MOLECULAR THERAPY 19(9) 2011-09
    DOI: 10.1038/mt.2011.136
  • Establishment and Characterization of a Transgenic Mouse Model for In Vivo Imaging of Bmp4 Expression in the Pancreas
    Mayu Yasunaga, Nao Oumi, Mitsuhiko Osaki, Yasuhiro Kazuki, Tomoko Nakanishi, Mitsuo Oshimura, Kenzo Sato
    PLOS ONE 6(9) 2011-09
    DOI: 10.1371/journal.pone.0024956
  • 染色体工学を応用したがん抑制遺伝子領域3p21.3の同定(Evidence for a telomerase suppressor gene in the 3p21.3 region by using chromosome engineering)
    大平 崇人, 阿部 智志, 押村 光雄, 久郷 裕之
    日本癌学会総会記事 70回 2011-09
  • Dysregulation of Gene Expression in the Artificial Human Trisomy Cells of Chromosome 8 Associated with Transformed Cell Phenotypes
    Hisakatsu Nawata, Genro Kashino, Keizo Tano, Kazuhiro Daino, Yoshiya Shimada, Hiroyuki Kugoh, Mitsuo Oshimura, Masami Watanabe
    PLOS ONE 6(9) 2011-09
    DOI: 10.1371/journal.pone.0025319
  • 赤血球膜陰イオン交換輸送体(eAE1)膜ドメインの構造解析に向けた抗体の利用
    荒川 孝俊, 小林 貴美, 岩成 宏子, 日野 智也, 名倉 淑子, 波多江 日成子, 隈 博幸, Cameron Alexander, 浜窪 隆雄, 濱崎 直孝, 岩田 想, 小林 拓也, 村田 武士
    日本生化学会大会プログラム・講演要旨集 84回 2011-09
  • Gene dosage imbalance of human chromosome 21 in mouse embryonic stem cells differentiating to neurons
    Chi Chiu Wang, Yasuhiro Kazuki, Mitsuo Oshimura, Kazuho Ikeo, Takashi Gojobori
    GENE 481(2) 2011-08
    DOI: 10.1016/j.gene.2011.04.003
  • Stem Cell-Mediated Transfer of a Human Artificial Chromosome Ameliorates Muscular Dystrophy
    Francesco Saverio Tedesco, Hidetoshi Hoshiya, Giuseppe D'Antona, Mattia F. M. Gerli, Graziella Messina, Stefania Antonini, Rossana Tonlorenzi, Sara Benedetti, Libera Berghella, Yvan Torrente, Yasuhiro Kazuki, Roberto Bottinelli, Mitsuo Oshimura, Giulio Cossu
    SCIENCE TRANSLATIONAL MEDICINE 3(96) 2011-08
    DOI: 10.1126/scitranslmed.3002342
  • Lysosomal accumulation of Trk protein in brain of G(M1)-gangliosidosis mouse and its restoration by chemical chaperone
    Ayumi Takamura, Katsumi Higaki, Haruaki Ninomiya, Tomoko Takai, Junichiro Matsuda, Masami Iida, Kousaku Ohno, Yoshiyuki Suzuki, Eiji Nanba
    JOURNAL OF NEUROCHEMISTRY 118(3) 2011-08
    DOI: 10.1111/j.1471-4159.2011.07310.x
  • An ATP-binding cassette subfamily G full transporter is essential for the retention of leaf water in both wild barley and rice
    Guoxiong Chen, Takao Komatsuda, Jian Feng Ma, Christiane Nawrath, Mohammad Pourkheirandish, Akemi Tagiri, Yin-Gang Hu, Mohammad Sameri, Xinrong Li, Xin Zhao, Yubing Liu, Chao Li, Xiaoying Ma, Aidong Wang, Sudha Nair, Ning Wang, Akio Miyao, Shun Sakuma, Naoki Yamaji, Xiuting Zheng, Eviatar Nevo
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108(30) 2011-07
    DOI: 10.1073/pnas.1108444108
  • Chemical Chaperone Therapy: Chaperone Effect on Mutant Enzyme and Cellular Pathophysiology in beta-Galactosidase Deficiency
    Katsumi Higaki, Linjing Li, Udin Bahrudin, Soichiro Okuzawa, Ayumi Takamuram, Koichi Yamamoto, Kaori Adachi, Rubigilda C. Paraguison, Tomoko Takai, Hiroki Ikehata, Lika Tominaga, Ichiro Hisatome, Masami Iida, Seiichiro Ogawa, Junichiro Matsuda, Haruaki Ninomiya, Yasubumi Sakakibara, Kousaku Ohno, Yoshiyuki Suzuki, Eiji Nanba
    HUMAN MUTATION 32(7) 2011-07
    DOI: 10.1002/humu.21516
  • An "Exacerbate-reverse" Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease
    Andrew B. Munkacsi, Fannie W. Chen, Matthew A. Brinkman, Katsumi Higaki, Giselle Dominguez Gutierrez, Jagruti Chaudhari, Jacob V. Layer, Amy Tong, Martin Bard, Charles Boone, Yiannis A. Ioannou, Stephen L. Sturley
    JOURNAL OF BIOLOGICAL CHEMISTRY 286(27) 2011-07
    DOI: 10.1074/jbc.M111.227645
  • Covalent Structural Changes in Unfolded GroES That Lead to Amyloid Fibril Formation Detected by NMR INSIGHT INTO INTRINSICALLY DISORDERED PROTEINS
    Hisanori Iwasa, Shunsuke Meshitsuka, Kunihiro Hongo, Tomohiro Mizobata, Yasushi Kawata
    JOURNAL OF BIOLOGICAL CHEMISTRY 286(24) 2011-06
    DOI: 10.1074/jbc.M111.228445
  • MicroRNA-143 Regulates Human Osteosarcoma Metastasis by Regulating Matrix Metalloprotease-13 Expression
    Mitsuhiko Osaki, Fumitaka Takeshita, Yui Sugimoto, Nobuyoshi Kosaka, Yusuke Yamamoto, Yusuke Yoshioka, Eisuke Kobayashi, Tesshi Yamada, Akira Kawai, Toshiaki Inoue, Hisao Ito, Mitsuo Oshimura, Takahiro Ochiya
    MOLECULAR THERAPY 19(6) 2011-06
    DOI: 10.1038/mt.2011.53
  • The Domestication Syndrome Genes Responsible for the Major Changes in Plant Form in the Triticeae Crops
    Shun Sakuma, Bjorn Salomon, Takao Komatsuda
    PLANT AND CELL PHYSIOLOGY 52(5) 2011-05
    DOI: 10.1093/pcp/pcr025
  • Development of a Bioactive Fiber with immobilized Synthetic Peptides Designed from the Active Site of a Beetle Defensin
    Makoto Nakamura, Takashi Iwasaki, Seiji Tokino, Ai Asaoka, Minoru Yamakawa, Jun Ishibashi
    BIOMACROMOLECULES 12(5) 2011-05
    DOI: 10.1021/bm1014969
  • Identification of PITX1 as a TERT Suppressor Gene Located on Human Chromosome 5
    Dong-Lai Qi, Takahito Ohhira, Chikako Fujisaki, Toshiaki Inoue, Tsutomu Ohta, Mitsuhiko Osaki, Eriko Ohshiro, Tomomi Seko, Shinsuke Aoki, Mitsuo Oshimura, Hiroyuki Kugoh
    MOLECULAR AND CELLULAR BIOLOGY 31(8) 2011-04
    DOI: 10.1128/MCB.00470-10
  • Application of a Bacterial Artificial Chromosome Modification System for a Human Artificial Chromosome Vector
    Shigeyuki Yamaguchi, Ryosuke Niwa, Yasuhiro Kazuki, Tetsuya Ohbayashi
    YONAGO ACTA MEDICA 54(1) 2011-03
  • A Method for Producing Transgenic Cells Using a Multi-Integrase System on a Human Artificial Chromosome Vector
    Shigeyuki Yamaguchi, Yasuhiro Kazuki, Yuji Nakayama, Eiji Nanba, Mitsuo Oshimura, Tetsuya Ohbayashi
    PLOS ONE 6(2) 2011-02
    DOI: 10.1371/journal.pone.0017267
  • Refined human artificial chromosome vectors for gene therapy and animaltransgenesis.
    Kazuki, Y, Hoshiya,H, Takiguchi, M, Abe, S, Iida, Y, Osaki, M, Katoh, M, Hiratsuka, M, Shirayoshi, Y, Hiramatsu, K, Ueno, E, Kajitani, N, Yoshino, T, Kazuki, K, Ishihara, C, Takehara, S, Tsuji, S, Ejima, F, Toyoda, A, Sakaki, Y, Larionov, V, Kouprina, N, Oshimura, M
    Gene Therapy 18(4) 2011
    DOI: 10.1038/gt.2010.147
  • SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis
    Yanze Li, Haruka Matsumori, Yuji Nakayama, Mitsuhiko Osaki, Hirotada Kojima, Akihiro Kurimasa, Hisao Ito, Seiichi Mori, Motonobu Katoh, Mitsuo Oshimura, Toshiaki Inoue
    GENES TO CELLS 16(1) 2011-01
    DOI: 10.1111/j.1365-2443.2010.01460.x
  • Dual modification of a triple-stranded beta-helix nanotube with Ru and Re metal complexes to promote photocatalytic reduction of CO2
    Norihiko Yokoi, Yuki Miura, Chen-Yuang Huang, Nobuyuki Takatani, Hiroshi Inaba, Tomomi Koshiyama, Shuji Kanamaru, Fumio Arisaka, Yoshihito Watanabe, Susumu Kitagawa, Takafumi Ueno
    CHEMICAL COMMUNICATIONS 47(7) 2011
    DOI: 10.1039/c0cc03015e
  • 1SC-03 Crystal structure of nitric oxide reductase, a key enzyme in the molecular evolution of respiratory complex(1SC Structural Features and Molecular Evolution of Bioenergetic Enzymes,The 49th Annual Meeting of the Biophysical Society of Japan)
    Hino Tomoya, Matsumoto Yushi, Nagano Shingo, Sugimoto Hiroshi, Fukumori Yoshihiro, Murata Takeshi, Iwata So, Shiro Yoshitsugu
    Seibutsu Butsuri 51 2011
    DOI: 10.2142/biophys.51.S3_2
  • Towards structure determination for G protein-coupled receptor
    Kobayashi Takuya, Shiroishi Mitsunori, Shimamura Tatsuro, Yurugi Takami, Asada Hidetsugu, Hino Tomoya, Arakawa Takatoshi, Murata Takeshi, Nomura Norimichi, Iwata So
    Journal of Pharmacological Sciences 115 2011
  • Lysosomal storage causes cellular dysfunction in mucolipidosis II skin fibroblasts.
    Otomo T, Higaki K, Nanba E, Ozono K, Sakai N
    J Biol Chem 286 2011
  • Homology of two alien chromosomes during meiosis in wheat
    Cho Seong-Woo, Moritama Yosuke, Ishii Takayoshi, Kishii Masahiro, Tanaka Hiroyuki, Eltayeb Amin Elsadig, Tsujimoto Hisashi
    Chromosome Science 14(3+4) 2011
    DOI: 10.11352/scr.14.45
  • Effects of the cytidine analogue zebularine on wheat mitotic chromosomes
    Cho Seong-Woo, Ishii Takayoshi, Matsumoto Naoya, Tanaka Hiroyuki, Eltayeb Amin Elsadig, Tsujimoto Hisashi
    Chromosome Science 14(1+2) 2011
    DOI: 10.11352/scr.14.23
年別