鳥取大学 染色体工学研究センター

研究成果
所属するすべての研究者の論文を紹介

2009年

  • Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3
    Yusuke Sato, Azusa Yoshikawa, Masami Yamashita, Atsushi Yamagata, Shuya Fukai
    EMBO JOURNAL 28(24) 2009-12
    DOI: 10.1038/emboj.2009.345
  • A Potentially Versatile Nucleotide Hydrolysis Activity of Group II Chaperonin Monomers from Thermoplasma acidophilum
    Kentaro Noi, Hidenori Hirai, Kunihiro Hongo, Tomohiro Mizobata, Yasushi Kawata
    BIOCHEMISTRY 48(40) 2009-10
    DOI: 10.1021/bi900959c
  • Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
    Azusa Yoshikawa, Yusuke Sato, Masami Yamashita, Hisatoshi Mimura, Atsushi Yamagata, Shuya Fukai
    FEBS LETTERS 583(20) 2009-10
    DOI: 10.1016/j.febslet.2009.09.028
  • Gly192 at hinge 2 site in the chaperonin GroEL plays a pivotal role in the dynamic apical domain movement that leads to GroES binding and efficient encapsulation of substrate proteins.
    Machida K, Fujiwara R, Tanaka T, Sakane I, Hongo K, Mizobata T, Kawata Y
    Biochimica et biophysica acta 1794 2009-09
    DOI: 10.1016/j.bbapap.2008.12.003
  • Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models.
    Joshua A Kritzer, Shusei Hamamichi, J Michael McCaffery, Sandro Santagata, Todd A Naumann, Kim A Caldwell, Guy A Caldwell, Susan Lindquist
    Nature chemical biology 5(9) 2009-09
    DOI: 10.1038/nchembio.193
  • Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80
    Yusuke Sato, Azusa Yoshikawa, Hisatoshi Mimura, Masami Yamashita, Atsushi Yamagata, Shuya Fukai
    EMBO JOURNAL 28(16) 2009-08
    DOI: 10.1038/emboj.2009.160
  • Genetic Reconstruction of Mouse Spermatogonial Stem Cell Self-Renewal In Vitro by Ras-Cyclin D2 Activation
    Jiyoung Lee, Mito Kanatsu-Shinohara, Hiroko Morimoto, Yasuhiro Kazuki, Seiji Takashima, Mitsuo Oshimura, Shinya Toyokuni, Takashi Shinohara
    CELL STEM CELL 5(1) 2009-07
    DOI: 10.1016/j.stem.2009.04.020
  • Characteristics of novel insect defensin-based membrane-disrupting trypanocidal peptides.
    Yamage M, Yoshiyama M, Grab DJ, Kubo M, Iwasaki T, Kitani H, Ishibashi J, Yamakawa M
    Bioscience, biotechnology, and biochemistry 73(7) 2009-07
    DOI: 10.1271/bbb.90004
  • Allele-Specific Expression Analysis of PEG1/MEST in Head and Neck Squamous Cell Carcinomas
    Hideyuki Kataoka, Seiji Nakano, Yasuomi Kunimoto, Naoko Sugie, Mitsuhiko Osaki, Narikazu Uzawa, Mitsuaki A. Yoshida, Mitsuo Oshimura, Hiroya Kitano
    YONAGO ACTA MEDICA 52(2) 2009-06
  • Towards the Extension of Life-Span of a Human Somatic Stem Cells Using a Human Artificial Chromosome Carrying a Conditional Centromere
    Yuichi Iida, Jun-ichirou Ohzeki, Yasuhiro Kazuki, Hidetoshi Hoshiya, Masato Takiguchi, Masahiro Hayashi, Megumi Nakano, Hiroshi Masumoto, William C Earnshaw, Vladimir Larionov, Mitsuo Oshimura
    Molecular Therapy 17 2009-05
  • Correction of Duchenne Muscular Dystrophy in Induced Pluripotent Stem Cells Using a Human Artifical Chromosome
    Yasuhiro Kazuki, Masaharu Hiratsuka, Masato Takiguchi, Mitsuhiko Osaki, Hidetoshi Hoshiya, Kei Hiramatsu, Naoyo Kajitani, Toko Yoshino, Kanako Kazuki, Narumi Uno, Masato Nakagawa, Kazutoshi Takahashi, Shinya Yamanaka, Mitsuo Oshimura
    MOLECULAR THERAPY 17 2009-05
  • A Novel Human Artificial Chromosome Vector Derived from Chromosome 14 (14HAC): Higher Transgene Expression System Using Sub-Telomere Sequences
    Minoru Kakeda, Keiko Nagata, Akiko Sano, Kanako Osawa, Akiyo Okazaki, Shingo Shitara, Yasuhiro Kazuki, Mitsuo Oshimura, Kazuma Tomizuka
    MOLECULAR THERAPY 17 2009-05
  • SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest
    Toshiaki Inoue, Yuji Nakayama, Hidetoshi Yamada, Yanze C. Li, Shigeyuki Yamaguchi, Mitsuhiko Osaki, Akihiro Kurimasa, Masaharu Hiratsuka, Motonobu Katoh, Mitsuo Oshimura
    CELL CYCLE 8(8) 2009-04
    DOI: 10.4161/cc.8.8.8245
  • Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing
    Jung-Hyun Kim, Thomas Ebersole, Natalay Kouprina, Vladimir N. Noskov, Jun-Ichirou Ohzeki, Hiroshi Masumoto, Brankica Mravinac, Beth A. Sullivan, Adam Pavlicek, Sinisa Dovat, Svetlana D. Pack, Yoo-Wook Kwon, Patrick T. Flanagan, Dmitri Loukinov, Victor Lobanenkov, Vladimir Larionov
    GENOME RESEARCH 19(4) 2009-04
    DOI: 10.1101/gr.086496.108
  • Selective cancer cell cytotoxicity of enantiomeric 9-mer peptides derived from beetle defensins depends on negatively charged phosphatidylserine on the cell surface
    Takashi Iwasaki, Jun Ishibashi, Hiromitsu Tanaka, Mitsuru Sato, Ai Asaoka, DeMar Taylor, Minoru Yamakawa
    Peptides 30(4) 2009-04
    DOI: 10.1016/j.peptides.2008.12.019
  • Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity.
    Aaron D Gitler, Alessandra Chesi, Melissa L Geddie, Katherine E Strathearn, Shusei Hamamichi, Kathryn J Hill, Kim A Caldwell, Guy A Caldwell, Antony A Cooper, Jean-Christophe Rochet, Susan Lindquist
    Nature genetics 41(3) 2009-03
    DOI: 10.1038/ng.300
  • Enhanced apoptosis during early neuronal differentiation in mouse ES cells with autosomal imbalance
    Yoshiteru Kai, Chi Chiu Wang, Satoshi Kishigami, Yasuhiro Kazuki, Satoshi Abe, Masato Takiguchi, Yasuaki Shirayoshi, Toshiaki Inoue, Hisao Ito, Teruhiko Wakayama, Mitsuo Oshimura
    CELL RESEARCH 19(2) 2009-02
    DOI: 10.1038/cr.2008.305
  • A highly Stable and Nonintegrated Human Artificial Chromosome (HAC) Containing the 2.4 Mb Entire Human Dystrophin Gene
    Hidetoshi Hoshiya, Yasuhiro Kazuki, Satoshi Abe, Masato Takiguchi, Naoyo Kajitani, Yoshinori Watanabe, Toko Yoshino, Yasuaki Shirayoshi, Katsumi Higaki, Graziella Messina, Giulio Cossu, Mitsuo Oshimura
    MOLECULAR THERAPY 17(2) 2009-02
    DOI: 10.1038/mt.2008.253
  • Identification of the Chromatin Regions Coated by Non-coding Xist RNA
    K. Murakami, T. Ohhira, E. Oshiro, D. Qi, M. Oshimura, H. Kugoh
    CYTOGENETIC AND GENOME RESEARCH 125(1) 2009
    DOI: 10.1159/000207514
  • 2P-054 Characteristics of conformational changes and dynamics in unfolded state of GroES(Protein:Property,The 47th Annual Meeting of the Biophysical Society of Japan)
    Iwase Hisanori, Meshitsuka Shunsuke, Hongo Kunihiro, Mizobata Tomohiro, Kawata Yasushi
    Seibutsu Butsuri 49 2009
    DOI: 10.2142/biophys.49.S115_2
  • Mechanical unfolding of covalently linked GroES: Evidence of structural subunit intermediates
    Isao Sakane, Kunihiro Hongo, Tomohiro Mizobata, Yasushi Kawata
    PROTEIN SCIENCE 18(1) 2009-01
    DOI: 10.1002/pro.7
  • Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator
    Azusa Seto, Hiroaki Ikushima, Toshiyasu Suzuki, Yusuke Sato, Shuya Fukai, Keiko Yuki, Keiji Miyazawa, Kohei Miyazono, Ryuichiro Ishitani, Osamu Nureki
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 65(Pt 1) 2009-01
    DOI: 10.1107/S1744309108038219
  • Inhibition of autophagosome formation restores mitochondrial function in Mucolipidosis II and III skin fibroblasts.
    Otomo T, Higaki K, Nanba E, Ozono K, Sakai N
    Mol. Genet Metab 98 2009
  • Chaperone activity of bicyclic nojirimycin analogues for Gaucher mutations in comparison with N-(n-nonyl)Deoxynojirimycin.
    Luan Z, Higaki K, Aquilar-Moncayo M, Ninomiya H, Ohno K, Garca-Moreno MI, Ortiz Mellet C, Garca Fernndez JM, Suzuki Y
    ChemBioChem 10 2009
  • High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas
    Kazunori Kidani, Mitsuhiko Osaki, Takayuki Tamura, Kensaku Yamaga, Kohei Shomori, Kazuo Ryoke, Hisao Ito
    ORAL ONCOLOGY 45(1) 2009-01
    DOI: 10.1016/j.oraloncology.2008.03.016
  • Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure
    Agnieszka Banas, Takumi Teratani, Yusuke Yamamoto, Makoto Tokuhara, Fumitaka Takeshita, Mitsuhiko Osaki, Takashi Kato, Hitoshi Okochi, Takahiro Ochiya
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 24(1) 2009-01
    DOI: 10.1111/j.1440-1746.2008.05496.x
  • Multiple functions of short synthetic enantiomeric peptides based on beetle defensins
    Takashi Iwasaki, Jun Ishibashi, Masanori Kubo, DeMar Taylor, Minoru Yamakawa
    Bioscience, Biotechnology and Biochemistry 73(3) 2009
    DOI: 10.1271/bbb.80735
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