研究成果
2013年
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Highly stable maintenance of a mouse artificial chromosome in human cells and mice
Kanako Kazuki, Shoko Takehara, Narumi Uno, Natsuko Imaoka, Satoshi Abe, Masato Takiguchi, Kei Hiramatsu, Mitsuo Oshimura, Yasuhiro Kazuki
Biochemical and Biophysical Research Communications 442(1-2)
2013-12-06
DOI:
10.1016/j.bbrc.2013.10.171
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Bilberry Anthocyanins Neutralize the Cytotoxicity of Co-Chaperonin GroES Fibrillation Intermediates
Hisanori Iwasa, Hiroshi Kameda, Naoya Fukui, Sakiho Yoshida, Kunihiro Hongo, Tomohiro Mizobata, Saori Kobayashi, Yasushi Kawata
BIOCHEMISTRY 52(51)
2013-12
DOI:
10.1021/bi401135j
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Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
Akihisa Shimizu, Ai Kawana-Tachikawa, Atsushi Yamagata, Chungyong Han, Dayong Zhu, Yusuke Sato, Hitomi Nakamura, Tomohiko Koibuchi, Jonathan Carlson, Eric Martin, Chanson J. Brumme, Yi Shi, George F. Gao, Zabrina L. Brumme, Shuya Fukai, Aikichi Iwamoto
SCIENTIFIC REPORTS 3
2013-11
DOI:
10.1038/srep03097
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Chronic inflammation-derived nitric oxide causes conversion of human colonic adenoma cells into adenocarcinoma cells
Tazawa H, Kawaguchi T, Kobayashi T, Kuramitsu Y, Wada S, Satomi Y, Nishino H, Kobayashi M, Kanda Y, Osaki M, Kitagawa T, Hosokawa M, Okada F
Experimental Cell Research 319(18)
2013-11
DOI:
10.1016/j.yexcr.2013.08.006
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Probing the Dynamic Process of Encapsulation in Escherichia coli GroEL
Toshifumi Mizuta, Kasumi Ando, Tatsuya Uemura, Yasushi Kawata, Tomohiro Mizobata
PLOS ONE 8(10)
2013-10
DOI:
10.1371/journal.pone.0078135
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Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression
Hideki Yamashita, Koji Endo, Chikako Takeda, Ryota Teshima, Mitsuhiko Osaki, Haruhiko Yoshida
SKELETAL RADIOLOGY 42(10)
2013-10
DOI:
10.1007/s00256-013-1641-4
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Variation in the wheat AP2 homoeologs, the genes underlying lodicule development
Shunzong Ning, Ning Wang, Shun Sakuma, Mohammad Pourkheirandish, Takato Koba, Takao Komatsuda
BREEDING SCIENCE 63(3)
2013-09
DOI:
10.1270/jsbbs.63.255
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Six-rowed spike4 (Vrs4) controls spikelet determinacy and row-type in barley
Ravi Koppolu, Nadia Anwar, Shun Sakuma, Akemi Tagiri, Udda Lundqvist, Mohammad Pourkheirandish, Twan Rutten, Christiane Seiler, Axel Himmelbach, Ruvini Ariyadasa, Helmy Mohamad Youssef, Nils Stein, Nese Sreenivasulu, Takao Komatsuda, Thorsten Schnurbusch
Proceedings of the National Academy of Sciences of the United States of America 110(32)
2013-08-06
DOI:
10.1073/pnas.1221950110
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Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver
Mari Hashimoto, Kaoru Kobayashi, Mio Watanabe, Yasuhiro Kazuki, Shoko Takehara, Asumi Inaba, Shin-ichiro Nitta, Naoto Senda, Mitsuo Oshimura, Kan Chiba
JOURNAL OF LIPID RESEARCH 54(8)
2013-08
DOI:
10.1194/jlr.M033464
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Generation of functional antibodies for mammalian membrane protein crystallography
Tomoya Hino, So Iwata, Takeshi Murata
CURRENT OPINION IN STRUCTURAL BIOLOGY 23(4)
2013-08
DOI:
10.1016/j.sbi.2013.04.007
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The luminal progenitor compartment of the normal human mammary gland constitutes a unique site of telomere dysfunction.
Nagarajan Kannan, Nazmul Huda, Liren Tu, Droumeva R, Aubert G, Chavez E, Ryan Brinkman, Lansdorp P, Emerman J, Abe S, Connie Eaves, Gilley D
Stem cell reports
2013-06-04
DOI:
10.1016/j.stemcr.2013.04.003
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Comparison of Genomic and Epigenomic Expression in Monozygotic Twins Discordant for Rett Syndrome
Kunio Miyake, Chunshu Yang, Yohei Minakuchi, Kenta Ohori, Masaki Soutome, Takae Hirasawa, Yasuhiro Kazuki, Noboru Adachi, Seiko Suzuki, Masayuki Itoh, Yu-ichi Goto, Tomoko Andoh, Hiroshi Kurosawa, Mitsuo Oshimura, Masayuki Sasaki, Atsushi Toyoda, Takeo Kubota
PLOS ONE 8(6)
2013-06
DOI:
10.1371/journal.pone.0066729
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Decreased PITX1 gene expression in human cutaneous malignant melanoma and its clinicopathological significance
Mitsuhiko Osaki, Hikari Chinen, Yuichi Yoshida, Takahito Ohhira, Naohiro Sunamura, Osamu Yamamoto, Hisao Ito, Mitsuo Oshimura, Hiroyuki Kugoh
EUROPEAN JOURNAL OF DERMATOLOGY 23(3)
2013-05
DOI:
10.1684/ejd.2013.2021
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Structure, transcription and post-transcriptional regulation of the bread wheat orthologs of the barley cleistogamy gene Cly1
Shunzong Ning, Ning Wang, Shun Sakuma, Mohammad Pourkheirandish, Jianzhong Wu, Takashi Matsumoto, Takato Koba, Takao Komatsuda
THEORETICAL AND APPLIED GENETICS 126(5)
2013-05
DOI:
10.1007/s00122-013-2052-6
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Identification of the Control Region of Pancreatic Expression of Bmp4 In Vitro and In Vivo
Mayu Yasunaga, Eiji Masui, Asami Oji, Atsumi Soma, Mitsuhiko Osaki, Tomoko Nakanishi, Kenzo Sato
PLOS ONE 8(4)
2013-04
DOI:
10.1371/journal.pone.0061821
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Wide hybridization between oat and pearl millet belonging to different subfamilies of Poaceae
Takayoshi Ishii, Hiroyuki Tanaka, Amin Elsadig Eltayeb, Hisashi Tsujimoto
PLANT REPRODUCTION 26(1)
2013-03
DOI:
10.1007/s00497-012-0205-4
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Nap1 regulates proper CENP-B binding to nucleosomes
Hiroaki Tachiwana, Yuta Miya, Nobuaki Shono, Jun-ichirou Ohzeki, Akihisa Osakabe, Koichiro Otake, Vladimir Larionov, William C. Earnshaw, Hiroshi Kimura, Hiroshi Masumoto, Hitoshi Kurumizaka
NUCLEIC ACIDS RESEARCH 41(5)
2013-03
DOI:
10.1093/nar/gks1464
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New Vectors for Gene Delivery: Human and Mouse Artificial Chromosomes
Mitsuo Oshimura, Yasuhiro Kazuki, Yuichi Iida, Narumi Uno
eLS
2013-02-15
DOI:
10.1002/9780470015902.a0024474
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Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans
Yasuhiro Kazuki, Kaoru Kobayashi, Sasitorn Aueviriyavit, Takeshi Oshima, Yoshimi Kuroiwa, Yasuko Tsukazaki, Naoto Senda, Hiroki Kawakami, Sumio Ohtsuki, Satoshi Abe, Masato Takiguchi, Hidetoshi Hoshiya, Naoyo Kajitani, Shoko Takehara, Kinya Kubo, Tetsuya Terasaki, Kan Chiba, Kazuma Tomizuka, Mitsuo Oshimura
HUMAN MOLECULAR GENETICS 22(3)
2013-02
DOI:
10.1093/hmg/dds468
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An induced pluripotent stem cell-mediated and integration-free factor VIII expression system
Yuwna Yakura, Chie Ishihara, Hajime Kurosaki, Yasuhiro Kazuki, Norio Komatsu, Yoshiaki Okada, Takefumi Doi, Hiroyuki Takeya, Mitsuo Oshimura
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 431(2)
2013-02
DOI:
10.1016/j.bbrc.2012.12.096
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Divergence of expression pattern contributed to neofunctionalization of duplicated HD-Zip I transcription factor in barley
Shun Sakuma, Mohammad Pourkheirandish, Goetz Hensel, Jochen Kumlehn, Nils Stein, Akemi Tagiri, Naoki Yamaji, Jian Feng Ma, Hidenori Sassa, Takato Koba, Takao Komatsuda
NEW PHYTOLOGIST 197(3)
2013-02
DOI:
10.1111/nph.12068
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Inorganic Design of Protein Assemblies as Supramolecular Platforms
Nusrat J. M. Sanghamitra, Hiroshi Inaba, Susumu Kitagawa, Takafumi Ueno
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS 23(1)
2013-01
DOI:
10.1007/s10904-012-9728-2
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An eceriferum locus, cer-zv, is associated with a defect in cutin responsible for water retention in barley (Hordeum vulgare) leaves
Chao Li, Aidong Wang, Xiaoying Ma, Mohammad Pourkheirandish, Shun Sakuma, Ning Wang, Shunzong Ning, Eviatar Nevo, Christiane Nawrath, Takao Komatsuda, Guoxiong Chen
Theoretical and Applied Genetics 126(3)
2013
DOI:
10.1007/s00122-012-2007-3
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3P005 Crystal structure of a hemophore hasA secreted by Yersinia pseudotuberclosis shows a novel heme binding mode(01A. Protein: Structure,Poster)
Kanadani Masahiro, Muroki Toshiki, Ishimaru Yukie, Wada Saki, Sato Takehiro, Ozaki Shin-ichi, Hino Tomoya, Nagano Shingo
Seibutsu Butsuri 53(1)
2013
DOI:
10.2142/biophys.53.S212_5
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2P001 Crystal structure of a mutant flavoenzyme RebC and construction mechanism of indolocarbazole aglycone structure(01A. Protein: Structure,Poster)
Itatani Hayate, Izumo Eiyu, Kageyama Saki, Kurozumi Sayaka, Onaka Hiroyasu, Asamizu Shumpei, Hino Tomoya, Nagano Shingo
Seibutsu Butsuri 53(1)
2013
DOI:
10.2142/biophys.53.S159_1
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The chaperone activity and toxicity of ambroxol on GD cells and normal mice.
Luan Z, Higaki K, Nanba E, Suzuki Y, Ohno K
Brain Dev 35
2013
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A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis
Tomoko Takai, Katsumi Higaki, Matilde Aguilar-Moncayo, Teresa Mena-Barragn, Yuki Hirano, Kei Yura, Liang Yu, Haruaki Ninomiya, M. Isabel Garca-Moreno, Yasubumi Sakakibara, Kousaku Ohno, Eiji Nanba, Carmen Ortiz Mellet, Jos M. Garca Fernndez, Yoshiyuki Suzuki
Molecular Therapy 21(3)
2013
DOI:
10.1038/mt.2012.263
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wo candidate molecules for chemical chaperone therapy for GM1-gangliosidosis.
Higaki K, Ninomiya H, Suzuki Y, Nanba E
Future Med Chem 5
2013
