鳥取大学 染色体工学研究センター

研究成果
所属するすべての研究者の論文を紹介

2021年

  • N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21
    Hiromitsu Toshikawa, Akihiro Ikenaka, Li Li, Yoko Nishinaka-Arai, Akira Niwa, Akira Ashida, Yasuhiro Kazuki, Tatsutoshi Nakahata, Hiroshi Tamai, David W. Russell, Megumu K. Saito
    Scientific Reports 11(1) 2021-12
    DOI: 10.1038/s41598-021-96697-7
  • Turn-On Fluorescent Probe Based on a Dansyl Triarginine Peptide for Ganglioside Imaging
    Kazunori Matsuura, Koichi Hisamoto, Tomoya Tanaka, Ryota Sakamoto, Mizuki Okazaki, Hiroshi Inaba
    ACS Organic & Inorganic Au 1(2) 2021-12-01
    DOI: 10.1021/acsorginorgau.1c00013
  • Histidine-rich protein 2: a new pathogenic factor of Plasmodium falciparum malaria
    Takashi Iwasaki, Mayu Shimoda, Haru Kanayama, Tsuyoshi Kawano
    bioRxiv 2021-11-19
    DOI: 10.1101/2021.11.19.469193
  • Quantitative prediction of P‐glycoprotein‐mediated drug–drug interactions and intestinal absorption using humanized mice
    Taiji Miyake, Haruka Tsutsui, Kenta Haraya, Tatsuhiko Tachibana, Kayoko Morimoto, Shoko Takehara, Miho Ayabe, Kaoru Kobayashi, Yasuhiro Kazuki
    British Journal of Pharmacology 178(21) 2021-11
    DOI: 10.1111/bph.15612
  • Effect of Zebularine on Chromosomal Association between Meiotic Homoeologous Chromosomes in Wheat Genetic Background (Triticum aestivum L.)
    Seong-Woo Cho, Takayoshi Ishii, Hisashi Tsujimoto
    Korean J. Crop Sci. 2021-11
    DOI: 10.7740/kjcs.2021.66.4.318
  • Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice.
    Satoshi Abe, Kazuhisa Honma, Akane Okada, Kanako Kazuki, Hiroshi Tanaka, Takeshi Endo, Kayoko Morimoto, Takashi Moriwaki, Shusei Hamamichi, Yuji Nakayama, Teruhiko Suzuki, Shoko Takehara, Mitsuo Oshimura, Yasuhiro Kazuki
    Scientific reports 11(1) 2021-10-08
    DOI: 10.1038/s41598-021-99535-y
  • Development and regeneration of wheat–rice hybrid zygotes produced by in vitro fertilization system
    Tety Maryenti, Takayoshi Ishii, Takashi Okamoto
    New Phytologist 2021-10-07
    DOI: 10.1111/nph.17747
  • Establishment of an Antibody Specific for AMIGO2 Improves Immunohistochemical Evaluation of Liver Metastases and Clinical Outcomes in Patients with Colorectal Cancer
    Keisuke Goto, Mitsuhiko Osaki, Runa Izutsu, Hiroshi Tanaka, Ryo Sasaki, Akimitsu Tanio, Hiroyuki Satofuka, Yasuhiro Kazuki, Manabu Yamamoto, Hiroyuki Kugoh, Hisao Ito, Mitsuo Oshimura, Yoshiyuki Fujiwara, Futoshi Okada
    2021-10-05
    DOI: 10.21203/rs.3.rs-934233/v1
  • Molecular Basis for Two Stereoselective Diels–Alderases that Produce Decalin Skeletons**
    Keisuke Fujiyama, Naoki Kato, Suyong Re, Kiyomi Kinugasa, Kohei Watanabe, Ryo Takita, Toshihiko Nogawa, Tomoya Hino, Hiroyuki Osada, Yuji Sugita, Shunji Takahashi, Shingo Nagano
    Angewandte Chemie 133(41) 2021-10-04
    DOI: 10.1002/ange.202106186
  • Inside Cover: Molecular Basis for Two Stereoselective Diels–Alderases that Produce Decalin Skeletons (Angew. Chem. Int. Ed. 41/2021)
    Keisuke Fujiyama, Naoki Kato, Suyong Re, Kiyomi Kinugasa, Kohei Watanabe, Ryo Takita, Toshihiko Nogawa, Tomoya Hino, Hiroyuki Osada, Yuji Sugita, Shunji Takahashi, Shingo Nagano
    Angewandte Chemie International Edition 60(41) 2021-10-04
    DOI: 10.1002/anie.202109381
  • Innentitelbild: Molecular Basis for Two Stereoselective Diels–Alderases that Produce Decalin Skeletons (Angew. Chem. 41/2021)
    Keisuke Fujiyama, Naoki Kato, Suyong Re, Kiyomi Kinugasa, Kohei Watanabe, Ryo Takita, Toshihiko Nogawa, Tomoya Hino, Hiroyuki Osada, Yuji Sugita, Shunji Takahashi, Shingo Nagano
    Angewandte Chemie 133(41) 2021-10-04
    DOI: 10.1002/ange.202109381
  • Infiltration of CD204-overexpressing Macrophages Contributes to the Progression of Stage II and III Colorectal Cancer.
    Yoichiro Tada, Yoshiaki Matsumi, Kazushi Hara, Wataru Miyauchi, Ken Sugesawa, Chihiro Uejima, Akimitsu Tanio, Kyoichi Kihara, Manabu Yamamoto, Shuichi Takano, Teruhisa Sakamoto, Yuji Nakayama, Toshimichi Hasegawa, Yoshiyuki Fujiwara
    Anticancer research 41(10) 2021-10
    DOI: 10.21873/anticanres.15299
  • PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes.
    Takahito Ohira, Suguru Nakagawa, Jumpei Takeshita, Hiroyuki Aburatani, Hiroyuki Kugoh
    Scientific reports 11(1) 2021-09-15
    DOI: 10.1038/s41598-021-97791-6
  • Evaluation of Parent- and Metabolite-Induced Mitochondrial Toxicities Using CYP-Introduced HepG2 cells
    Akinori Takemura, Simin Gong, Tomoyuki Sato, Moemi Kawaguchi, Shuichi Sekine, Yasuhiro Kazuki, Toru Horie, Kousei Ito
    Journal of Pharmaceutical Sciences 110(9) 2021-09
    DOI: 10.1016/j.xphs.2021.06.001
  • Modulation of Microtubule Properties and Functions by Encapsulation of Nanomaterials Using a Tau-Derived Peptide
    Hiroshi Inaba, Kazunori Matsuura
    Bulletin of the Chemical Society of Japan 94(8) 2021-08-15
    DOI: 10.1246/bcsj.20210202
  • The Evolutionary Dynamics of Repetitive DNA and Its Impact on the Genome Diversification in the Genus Sorghum
    Yi-Tzu Kuo, Takayoshi Ishii, Jörg Fuchs, Wei-Hsun Hsieh, Andreas Houben, Yann-Rong Lin
    Frontiers in Plant Science 12 2021-08-12
    DOI: 10.3389/fpls.2021.729734
  • A SARS-CoV-2 Antibody Broadly Neutralizes SARS-related Coronaviruses and Variants by Coordinated Recognition of a Virus Vulnerable Site
    Taishi Onodera, Shunsuke Kita, Yu Adachi, Saya Moriyama, Akihiko Sato, Takao Nomura, Shuhei Sakakibara, Takeshi Inoue, Takashi Tadokoro, Yuki Anraku, Kohei Yumoto, Cong Tian, Hideo Fukuhara, Michihito Sasaki, Yasuko Orba, Nozomi Shiwa, Naoko Iwata, Noriyo Nagata, Tateki Suzuki, Jiei Sasaki, Tsuyoshi Sekizuka, Keisuke Tonouchi, Lin Sun, Shuetsu Fukushi, Hiroyuki Satofuka, Yasuhiro Kazuki, Mitsuo Oshimura, Tomohiro Kurosaki, Makoto Kuroda, Yoshiharu Matsuura, Tadaki Suzuki, Hirofumi Sawa, Takao Hashiguchi, Katsumi Maenaka, Yoshimasa Takahashi
    Immunity 54(10) 2021-08
    DOI: 10.1016/j.immuni.2021.08.025
  • Water Stress Activates The Expression of Abscisic Acid Transporter, VuABCG25, in Cowpea [Vigna unguiculata (L.)Walp.]
    Takashi YUASA, Yoshiharu KUBO, Wataru FUJIMAKI, Takayoshi ISHII
    Cryobiology and Cryotechnology 67(1) 2021-08
  • Human chromosome 3p21.3 carries TERT transcriptional regulators in pancreatic cancer.
    Takuki Yagyu, Takahito Ohira, Ryutaro Shimizu, Masaki Morimoto, Yuki Murakami, Takehiko Hanaki, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Teruhisa Sakamoto, Yoshiyuki Fujiwara, Hiroyuki Kugoh
    Scientific reports 11(1) 2021-07-28
    DOI: 10.1038/s41598-021-94711-6
  • A New Intestinal Model for Analysis of Drug Absorption and Interactions Considering Physiological Translocation of Contents
    Satoshi Asano, Aoi Yoshitomo, Shizuka Hozuki, Hiromi Sato, Yasuhiro Kazuki, Akihiro Hisaka
    Drug Metabolism and Disposition 49(7) 2021-07
    DOI: 10.1124/dmd.121.000361
  • In vivo evaluation of intestinal human CYP3A inhibition by macrolide antibiotics in CYP3A-humanised mice.
    Genki Minegishi, Yasuhiro Kazuki, Shin-Ichiro Nitta, Atsushi Miyajima, Hidetaka Akita, Kaoru Kobayashi
    Xenobiotica; the fate of foreign compounds in biological systems 51(7) 2021-07
    DOI: 10.1080/00498254.2021.1921314
  • 染色体工学技術を応用した膵がんにおけるテロメラーゼ抑制領域3p21.3の同定
    柳生 拓輝, 大平 崇人, 花木 武彦, 木原 恭一, 松永 知之, 山本 学, 徳安 成郎, 坂本 照尚, 久郷 裕之, 藤原 義之
    日本消化器外科学会総会 76回 2021-07
  • Antitumor Effect of 5-Aminolevulinic Acid Through Ferroptosis in Esophageal Squamous Cell Carcinoma.
    Yuji Shishido, Masataka Amisaki, Yoshiaki Matsumi, Haruna Yakura, Yuji Nakayama, Wataru Miyauchi, Kozo Miyatani, Tomoyuki Matsunaga, Takehiko Hanaki, Kyoichi Kihara, Manabu Yamamoto, Naruo Tokuyasu, Shuichi Takano, Teruhisa Sakamoto, Soichiro Honjo, Toshimichi Hasegawa, Yoshiyuki Fujiwara
    Annals of surgical oncology 28(7) 2021-07
    DOI: 10.1245/s10434-020-09334-4
  • Structural basis for specific recognition of K6-linked polyubiquitin chains by the TAB2 NZF domain
    Yanjun Li, Kei Okatsu, Shuya Fukai, Yusuke Sato
    Biophysical Journal 2021-07
    DOI: 10.1016/j.bpj.2021.06.037
  • Genome-wide identification of loci modifying spike-branching in tetraploid wheat.
    Gizaw M Wolde, Mona Schreiber, Corinna Trautewig, Axel Himmelbach, Shun Sakuma, Martin Mascher, Thorsten Schnurbusch
    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 134(7) 2021-07
    DOI: 10.1007/s00122-020-03743-5
  • Novel Loci for Kernel Hardness Appeared as a Response to Heat and Combined Heat-Drought Conditions in Wheat Harboring Aegilops tauschii Diversity
    Gamila Mohamed Idris Elhadi, Nasrein Mohamed Kamal, Yasir Serag Alnor Gorafi, Yuji Yamasaki, Yusuke Ban, Keita Kato, Izzat Sidahmed Ali Tahir, Takayoshi Ishii, Hiroyuki Tanaka, Hisashi Tsujimoto
    Agronomy 11(6) 2021-05-25
    DOI: 10.3390/agronomy11061061
  • Direct protein delivery into intact plant cells using polyhistidine peptides
    Yoshino Tanaka, Yoshihiko Nanasato, Kousei Omura, Keita Endoh, Tsuyoshi Kawano, Takashi Iwasaki
    Bioscience, Biotechnology, and Biochemistry 85(6) 2021-05-25
    DOI: 10.1093/bbb/zbab055
  • Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress.
    An Cheng, Yi-Fei Wang, Yasuharu Shinoda, Ichiro Kawahata, Tetsunori Yamamoto, Wen-Bin Jia, Hanae Yamamoto, Tomohiro Mizobata, Yasushi Kawata, Kohji Fukunaga
    Acta pharmacologica Sinica 43(3) 2021-05-02
    DOI: 10.1038/s41401-021-00675-8
  • A novel all-in-one conditional knockout system uncovered an essential role of DDX1 in ribosomal RNA processing
    Teruhiko Suzuki, Eiji Katada, Yuki Mizuoka, Satoko Takagi, Yasuhiro Kazuki, Mitsuo Oshimura, Mayumi Shindo, Takahiko Hara
    Nucleic Acids Research 49(7) 2021-04-19
    DOI: 10.1093/nar/gkaa1296
  • An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3
    Naoya Fukui, Hanae Yamamoto, Moe Miyabe, Yuki Aoyama, Kunihiro Hongo, Tomohiro Mizobata, Ichiro Kawahata, Yasushi Yabuki, Yasuharu Shinoda, Kohji Fukunaga, Yasushi Kawata
    Journal of Biological Chemistry 296 2021-04
    DOI: 10.1016/j.jbc.2021.100663
  • Fluorescence Correlation Spectroscopy Analysis of Effect of Molecular Crowding on Self-Assembly of β-Annulus Peptide into Artificial Viral Capsid
    Risako Kobayashi, Hiroshi Inaba, Kazunori Matsuura
    International Journal of Molecular Sciences 22(9) 2021-04
    DOI: 10.3390/ijms22094754
  • Directional Propulsion of DNA Microspheres Based on Light-Induced Asymmetric Growth of Peptide Nanofibers
    Hiroshi Inaba, Kenji Hatta, Kazunori Matsuura
    ACS Applied Bio Materials 4(7) 2021-04
    DOI: 10.1021/acsabm.1c00146
  • AMIGO2 as a novel indicator of liver metastasis in patients with colorectal cancer.
    Akimitsu Tanio, Hiroaki Saito, Masataka Amisaki, Kazushi Hara, Ken Sugezawa, Chihiro Uejima, Yoichiro Tada, Kyoichi Kihara, Manabu Yamamoto, Kanae Nosaka, Ryo Sasaki, Mitsuhiko Osaki, Futoshi Okada, Yoshiyuki Fujiwara
    Oncology letters 21(4) 2021-04
    DOI: 10.3892/ol.2021.12539
  • Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells
    Satoru Iwado, Satoshi Abe, Mitsuo Oshimura, Yasuhiro Kazuki, Yoshihiro Nakajima
    International Journal of Molecular Sciences 22(6) 2021-03-11
    DOI: 10.3390/ijms22062843
  • Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling.
    Yasuhiro Kazuki, Narumi Uno, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Yuwna Yakura, Chiaki Sawada, Shuta Takata, Masaki Sugawara, Yuichi Nagashima, Akane Okada, Masaharu Hiratsuka, Mitsuhiko Osaki, Giulia Ferrari, Francesco Saverio Tedesco, Satoshi Nishikawa, Ken Fukumoto, Shin-Ichiro Takayanagi, Atsushi Kunisato, Shin Kaneko, Mitsuo Oshimura, Kazuma Tomizuka
    Molecular therapy. Nucleic acids 23 2021-03-05
    DOI: 10.1016/j.omtn.2020.12.012
  • ヒト胃癌細胞が分泌するAmigo2包含エクソソームは、胃癌細胞と肝内皮細胞との接着能を亢進させる
    井筒 瑠奈, 鄭 朱蒙パトリック, 根本 英幸, 石川 瑞穂, 尾崎 充彦, 岡田 太
    日本病理学会会誌 110(1) 2021-03
  • Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats.
    Toshihiro Kobayashi, Teppei Goto, Mami Oikawa, Makoto Sanbo, Fumika Yoshida, Reiko Terada, Naoko Niizeki, Naoyo Kajitani, Kanako Kazuki, Yasuhiro Kazuki, Shinichi Hochi, Hiromitsu Nakauchi, M Azim Surani, Masumi Hirabayashi
    Nature communications 12(1) 2021-02-26
    DOI: 10.1038/s41467-021-21557-x
  • Novel method for screening functional antibody with comprehensive analysis of its immunoliposome.
    Shusei Hamamichi, Takeshi Fukuhara, Izumi O Umeda, Hirofumi Fujii, Nobutaka Hattori
    Scientific reports 11(1) 2021-02-25
    DOI: 10.1038/s41598-021-84043-w
  • Inflammation-related Carcinogenesis: Lessons from Animal Models to Clinical Aspects.
    Okada F, Izutsu R, Goto K, Osaki M
    Cancers 13(4) 2021-02
    DOI: 10.3390/cancers13040921
  • Yield Potential and Variability of Teff (Eragrostis tef (Zucc.) Trotter) Germplasms under Intensive and Conventional Management Conditions
    Muluken Bayable, Atsushi Tsunekawa, Nigussie Haregeweyn, Getachew Alemayehu, Wataru Tsuji, Mitsuru Tsubo, Enyew Adgo, Asaminew Tassew, Takayoshi Ishii, Fekremariam Asaregew, Tsugiyuki Masunaga
    Agronomy 11(2) 2021-01-24
    DOI: 10.3390/agronomy11020220
  • Establishment of FXS-A9 panel with a single human X chromosome from fragile X syndrome-associated individual.
    Yuji Nakayama, Kaori Adachi, Nofirifumi Shioda, Shoya Maeta, Eiji Nanba, Hiroyuki Kugoh
    Experimental cell research 398(2) 2021-01-15
    DOI: 10.1016/j.yexcr.2020.112419
  • Corrigendum to "Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling" [Biochem. Biophys. Res. Commun. 524 (1) (2020) 1-7].
    Satoshi Yamanaka, Yusuke Sato, Daisuke Oikawa, Eiji Goto, Shuya Fukai, Fuminori Tokunaga, Hirotaka Takahashi, Tatsuya Sawasaki
    Biochemical and biophysical research communications 536 2021-01-15
    DOI: 10.1016/j.bbrc.2020.12.045
  • Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons.
    Ichiro Kawahata, Tomoki Sekimori, Haoyang Wang, Yanyan Wang, Toshikuni Sasaoka, Luc Bousset, Ronald Melki, Tomohiro Mizobata, Yasushi Kawata, Kohji Fukunaga
    Biomedicines 9(1) 2021-01-08
    DOI: 10.3390/biomedicines9010049
  • Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification.
    Shiori Matsuo, Yoko Nishinaka-Arai, Yasuhiro Kazuki, Mitsuo Oshimura, Tatsutoshi Nakahata, Akira Niwa, Megumu K Saito
    PloS one 16(3) 2021
    DOI: 10.1371/journal.pone.0247595
  • CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome.
    Sefan Asamitsu, Yasushi Yabuki, Susumu Ikenoshita, Kosuke Kawakubo, Moe Kawasaki, Shingo Usuki, Yuji Nakayama, Kaori Adachi, Hiroyuki Kugoh, Kazuhiro Ishii, Tohru Matsuura, Eiji Nanba, Hiroshi Sugiyama, Kohji Fukunaga, Norifumi Shioda
    Science advances 7(3) 2021-01
    DOI: 10.1126/sciadv.abd9440
  • Functional peptide nanocapsules self-assembled from β-annulus peptides
    Hiroshi Inaba, Kazunori Matsuura
    Methods in Molecular Biology 2208 2021
    DOI: 10.1007/978-1-0716-0928-6_7
  • Newly Invented Micellized Vitamin K2 Recovered Prolonged Prothrombin Time under Obstructive Jaundice in Rats with Bile Duct Ligation.
    Yoshiki Hoshino, Takaaki Sugihara, Suguru Ikeda, Ryohei Tarumoto, Yukako Matsuki, Tsutomu Kanda, Takuji Iyama, Tomoaki Takata, Tomomitsu Matono, Takakazu Nagahara, Jun-Ichi Okano, Masaru Ueki, Masahiko Koda, Mitsuhiko Osaki, Futoshi Okada, Hajime Isomoto
    Journal of nutritional science and vitaminology 67(6) 2021
    DOI: 10.3177/jnsv.67.397
  • Application of CRISPR/Cas9 to visualize defined genomic sequences in fixed chromosomes and nuclei
    Takayoshi Ishii, Kiyotaka Nagaki, Andreas Houben
    Cytogenomics 2021
    DOI: 10.1016/b978-0-12-823579-9.00007-2
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