鳥取大学 染色体工学研究センター

研究成果
所属するすべての研究者の論文を紹介

2010年

  • 複数遺伝子の搭載が可能な改良型ヒト人工染色体(HAC)ベクターの開発
    山口 繁幸, 吉村 祐貴, 佐々木 勝嵩, 西田 直史, 香月 康宏, 押村 光雄, 大林 徹也
    日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 83回・33回 2010-12
  • ヒト人工染色体ベクターを用いた発生・分化バイオイメージングシステム
    吉村 祐貴, 山口 繁幸, 遠藤 志穂, 中島 芳浩, 香月 康宏, 近江谷 克裕, 押村 光雄, 大林 徹也
    日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 83回・33回 2010-12
  • Structural Basis of Biological N2O Generation by Bacterial Nitric Oxide Reductase
    Tomoya Hino, Yushi Matsumoto, Shingo Nagano, Hiroshi Sugimoto, Yoshihiro Fukumori, Takeshi Murata, So Iwata, Yoshitsugu Shiro
    SCIENCE 330(6011) 2010-12
    DOI: 10.1126/science.1195591
  • A Human Artificial Chromosome (HAC) with a conditional centromere
    Hiroshi Masumoto, Jun-ichirou Ohzeki, Megumi Nakano, Jan Bergmann, Vladimir Noskov, Natalay Kouprina, William Earnshaw, Vladimir Larionov
    Genes & genetic systems 85(6) 2010-12
  • Refined human artificial chromosome vectors for gene therapy and animal transgenesis.
    Kazuki Y, Hoshiya H, Takiguchi M, Abe S, Iida Y, Osaki M, Katoh M, Hiratsuka M, Shirayoshi Y, Hiramatsu K, Ueno E, Kajitani N, Yoshino T, Kazuki K, Ishihara C, Takehara S, Tsuji S, Ejima F, Toyoda A, Sakaki Y, Larionov V, Kouprina N, Oshimura M
    Gene therapy 2010-11-18
    DOI: 10.1038/gt.2010.147
  • A Fluorescent sp(2)-Iminosugar With Pharmacological Chaperone Activity for Gaucher Disease: Synthesis and Intracellular Distribution Studies
    Zhuo Luan, Katsumi Higaki, Matilde Aguilar-Moncayo, Linjing Li, Haruaki Ninomiya, Eiji Nanba, Kousaku Ohno, M. Isabel Garcia-Moreno, Carmen Ortiz Mellet, Jose M. Garcia Fernandez, Yoshiyuki Suzuki
    CHEMBIOCHEM 11(17) 2010-11
    DOI: 10.1002/cbic.201000323
  • Chromosome elimination by wide hybridization between Triticeae or oat plant and pearl millet: pearl millet chromosome dynamics in hybrid embryo cells
    Takayoshi Ishii, Toshie Ueda, Hiroyuki Tanaka, Hisashi Tsujimoto
    CHROMOSOME RESEARCH 18(7) 2010-11
    DOI: 10.1007/s10577-010-9158-3
  • An Altered Method of Feeding RNAi That Knocks Down Multiple Genes Simultaneously in the Nematode Caenorhabditis elegans
    Kenji Gouda, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 74(11) 2010-11
    DOI: 10.1271/bbb.100579
  • Human Artificial Chromosome with a Conditional Centromere for Gene Delivery and Gene Expression
    Yuichi Iida, Jung-Hyun Kim, Yasuhiro Kazuki, Hidetoshi Hoshiya, Masato Takiguchi, Masahiro Hayashi, Indri Erliandri, Hee-Sheung Lee, Alex Samoshkin, Hiroshi Masumoto, William C. Earnshaw, Natalay Kouprina, Vladimir Larionov, Mitsuo Oshimura
    DNA RESEARCH 17(5) 2010-10
    DOI: 10.1093/dnares/dsq020
  • Isolation of short peptide fragments from alpha-synuclein fibril core identifies a residue important for fibril nucleation: a possible implication for diagnostic applications.
    Yagi H, Takeuchi H, Ogawa S, Ito N, Sakane I, Hongo K, Mizobata T, Goto Y, Kawata Y
    Biochimica et biophysica acta 1804 2010-10
    DOI: 10.1016/j.bbapap.2010.07.007
  • ヒト人工染色体ベクターの利点とその応用
    山口 繁幸, 大林 徹也, 香月 康宏, 押村 光雄
    生化学 82(9) 2010-09
  • Construction of Robust Bio-nanotubes using the Controlled Self-Assembly of Component Proteins of Bacteriophage T4
    Norihiko Yokoi, Hiroshi Inaba, Makoto Terauchi, Adam Z. Stieg, Nusrat J. M. Sanghamitra, Tomomi Koshiyama, Katsuhide Yutani, Shuji Kanamaru, Fumio Arisaka, Tatsuo Hikage, Atsuo Suzuki, Takashi Yamane, James K. Gimzewski, Yoshihito Watanabe, Susumu Kitagawa, Takafumi Ueno
    SMALL 6(17) 2010-09
    DOI: 10.1002/smll.201000772
  • ヒト5番染色体上に存在する新規テロメレース抑制遺伝子の同定(Identification of a novel telomerase repressor gene on human chromosme 5)
    久郷 裕之, Qi Dong-Lai, 大平 崇人, 太田 力, 井上 敏昭, 押村 光雄
    日本癌学会総会記事 69回 2010-08
  • Human chromosome 5 carries a transcriptional regulator of human telomerase reverse transcriptase (hTERT)
    Dong-Lai Qi, Takahito Ohhira, Mitsuo Oshimura, Hiroyuki Kugoh
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 398(4) 2010-08
    DOI: 10.1016/j.bbrc.2010.07.003
  • Development of evaluation system for bioactive substances using human artificial chromosome-mediated osteocalcin gene expression
    Yusuke Takahashi, Saori Tsuji, Yasuhiro Kazuki, Makoto Noguchi, Ichiro Arifuku, Yukihiro Umebayashi, Tomoko Nakanishi, Mitsuo Oshimura, Kenzo Sato
    JOURNAL OF BIOCHEMISTRY 148(1) 2010-07
    DOI: 10.1093/jb/mvq030
  • Cysteine-rich protein 61 suppresses cell invasion via down-regulation of matrix metalloproteinase-7 expression in the human gastric carcinoma cell line MKN-45
    Mitsuhiko Osaki, Aiko Inaba, Kei Nishikawa, Yui Sugimoto, Kohei Shomori, Toshiaki Inoue, Mitsuo Oshimura, Hisao Ito
    MOLECULAR MEDICINE REPORTS 3(4) 2010-07
    DOI: 10.3892/mmr_00000322
  • Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.
    Satoshi Abe, Hiromi Tanaka, Tomomi Notsu, Shin-Ichi Horike, Chikako Fujisaki, Dong-Lai Qi, Takahito Ohhira, David Gilley, Mitsuo Oshimura, Hiroyuki Kugoh
    Genome integrity 1(1) 2010-05-26
    DOI: 10.1186/2041-9414-1-6
  • A gene delivery system with a human artificial chromosome vector based on migration of mesenchymal stem cells towards human glioblastoma HTB14 cells
    Yusuke Kinoshita, Hideki Kamitani, Mahabub Hasan Mamun, Brian Wasita, Yasuhiro Kazuki, Masaharu Hiratsuka, Mitsuo Oshimura, Takashi Watanabe
    NEUROLOGICAL RESEARCH 32(4) 2010-05
    DOI: 10.1179/174313209X455718
  • Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer
    Motonobu Katoh, Yasuhiro Kazuki, Kanako Kazuki, Naoyo Kajitani, Masato Takiguchi, Yuji Nakayama, Takafumi Nakamura, Mitsuo Oshimura
    BMC BIOTECHNOLOGY 10 2010-05
    DOI: 10.1186/1472-6750-10-37
  • C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease.
    Adam J Harrington, Shusei Hamamichi, Guy A Caldwell, Kim A Caldwell
    Developmental dynamics : an official publication of the American Association of Anatomists 239(5) 2010-05
    DOI: 10.1002/dvdy.22231
  • Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models
    Linhui Julie Su, Pavan K. Auluck, Tiago Fleming Outeiro, Esti Yeger-Lotem, Joshua A. Kritzer, Daniel F. Tardiff, Katherine E. Strathearn, Fang Liu, Songsong Cao, Shusei Hamamichi, Kathryn J. Hill, Kim A. Caldwell, George W. Bell, Ernest Fraenkel, Antony A. Cooper, Guy A. Caldwell, J. Michael McCaffery, Jean-Christophe Rochet, Susan Lindquist
    Disease Models & Mechanisms 3(3-4) 2010-03-08
    DOI: 10.1242/dmm.004267
  • Identification, Isolation and Characterization of HCN4-Positive Pacemaking Cells Derived from Murine Embryonic Stem Cells during Cardiac Differentiation
    Kumi Morikawa, Udin Bahrudin, Junichiro Miake, Osamu Igawa, Yasutaka Kurata, Yuji Nakayama, Yasuaki Shirayoshi, Ichiro Hisatome
    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY 33(3) 2010-03
    DOI: 10.1111/j.1540-8159.2009.02614.x
  • Duplication of a well-conserved homeodomain-leucine zipper transcription factor gene in barley generates a copy with more specific functions
    Shun Sakuma, Mohammad Pourkheirandish, Takashi Matsumoto, Takato Koba, Takao Komatsuda
    FUNCTIONAL & INTEGRATIVE GENOMICS 10(1) 2010-03
    DOI: 10.1007/s10142-009-0134-y
  • ユビキチン鎖の認識と選択的切断メカニズムの構造的理解
    深井 周也, 佐藤 裕介
    日本結晶学会誌 52(1) 2010-02-28
    DOI: 10.5940/jcrsj.52.20
  • Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy
    Yasuhiro Kazuki, Masaharu Hiratsuka, Masato Takiguchi, Mitsuhiko Osaki, Naoyo Kajitani, Hidetoshi Hoshiya, Kei Hiramatsu, Toko Yoshino, Kanako Kazuki, Chie Ishihara, Shoko Takehara, Katsumi Higaki, Masato Nakagawa, Kazutoshi Takahashi, Shinya Yamanaka, Mitsuo Oshimura
    MOLECULAR THERAPY 18(2) 2010-02
    DOI: 10.1038/mt.2009.274
  • Structural basis for the Rho-and phosphoinositide-dependent localization of the exocyst subunit Sec3
    Masami Yamashita, Kazuo Kurokawa, Yusuke Sato, Atsushi Yamagata, Hisatoshi Mimura, Azusa Yoshikawa, Ken Sato, Akihiko Nakano, Shuya Fukai
    Nature Structural and Molecular Biology 17(2) 2010-02
    DOI: 10.1038/nsmb.1722
  • Structural basis for the Rho- and phosphoinositide-dependent localization of the exocyst subunit Sec3
    Masami Yamashita, Kazuo Kurokawa, Yusuke Sato, Atsushi Yamagata, Hisatoshi Mimura, Azusa Yoshikawa, Ken Sato, Akihiko Nakano, Shuya Fukai
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 17(2) 2010-02
    DOI: 10.1038/nsmb.1722
  • Advantages and applications of human artificial chromosome vector

    Seikagaku 82(9) 2010
  • 1P065 Mutation effects of the residues that are critical to formation of GroES amyloid fibril intermediate(Protein:Property,The 48th Annual Meeting of the Biophysical Society of Japan)
    Iwasa Hisanori, Meshitsuka Shunsuke, Hongo Kunihiro, Mizobata Tomohiro, Kawata Yasushi
    Seibutsu Butsuri 50(2) 2010
    DOI: 10.2142/biophys.50.S30_4
  • The two faces of Janus: Recent studies on the characteristics of E. coli GroEL and its apical domain

    Seikagaku 82(7) 2010
  • Structural insight into the membrane insertion of tail-anchored proteins by Get3
    Atsushi Yamagata, Hisatoshi Mimura, Yusuke Sato, Masami Yamashita, Azusa Yoshikawa, Shuya Fukai
    GENES TO CELLS 15(1) 2010-01
    DOI: 10.1111/j.1365-2443.2009.01362.x
  • Chemical chaperone therapy: Luciferase assay for screening of β-galactosidase mutations.
    Li L, Higaki K, Ninomiya H, Luan Z, Iida M, Ogawa S, Suzuki Y, Ohno K, Nanba E
    Mol Genet Metab 101 2010
  • Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes
    Fumitaka Takeshita, Lubna Patrawala, Mitsuhiko Osaki, Ryou-u Takahashi, Yusuke Yamamoto, Nobuyoshi Kosaka, Masaki Kawamata, Kevin Kelnar, Andreas G. Bader, David Brown, Takahiro Ochiya
    MOLECULAR THERAPY 18(1) 2010-01
    DOI: 10.1038/mt.2009.207
  • Wide hybridization between Triticeae/Avenae plants and pearl millet: Dynamics of pearl millet chromosomes in hybrid embryo cells
    Ishii, T, Ueda, T., Tanaka, H., Tsujimoto, H.
    Advances in Chromosome Sciences; Vol. 3 2010
  • Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease.
    T A Yacoubian, S R Slone, A J Harrington, S Hamamichi, J M Schieltz, K A Caldwell, G A Caldwell, D G Standaert
    Cell death & disease 1 2010
    DOI: 10.1038/cddis.2009.4
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