鳥取大学における染色体医工学研究の歩み
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6e17267, 201117. Kim J.H., Kononenko A., Erliandri I., Kim T.A., Nakano M., Iida Y., Barrett J.C., Oshimura M., Masumoto H., Earnshaw W.C., Larionov V., Kouprina N.: Human artifi cial chromosome (HAC) vector with a conditional centromere for correction of genetic defi ciencies in human cells. Proc Natl Acad Sci USA, 201118. Kakeda M., Nagata K., Osawa K., Matsuno H., Hiratsuka M., Sano A., Okazaki A., Shitara S., Nishikawa S., Masuya A., Hata T., Wako S., Osaki M., Kazuki Y., Oshimura M., Tomizuka K.: A new chromosome 14-based human artificial chromosome (HAC) vector system for efficient transgene expression in human primary cells. Biochem Biophys Res Commun. 415:439-44.2011C: Tumor suppression(癌抑制)1. 押村光雄:マウスA9 蛋白質 核酸 酵素 33: 2411, 19882. 児井 稔,押村光雄:SiHa 蛋白質 核酸 酵素 33: 2540-2541, 19883. 堀川 泉,押村光雄:癌抑制染色体 BIOmedica, 4: 1104-1109, 19894. Koi M., Morita H., Yamada H., Satoh H., Barrett J.C., Oshimura M.: Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa. Mol. Carcinogen., 2: 12-21, 19895. 押村光雄,清水素行:がん抑制に働く染色体 BIOmedica, 4: 833-838, 19896. 押村光雄:染色体移入による癌抑制 実験医学 7: 1377-1381, 19897. Mori N., Yokota J., Oshimura M., Cavenee W.K., Mizoguchi H., Noguchi M., Shimosato Y., Sugimura T., Terada M.: Concordant deletions of chromosome 3p and loss of heterozygosity for chromosomes 13 and 17 in small cell lung carcinoma. Cancer Res., 49: 5130-5135, 19898. Nagashima, Y., Ohaki, Y., Umeda, M., Oshimura, M., Misugi, K.: Establishment and characterization of an immature epithelial cell line (ENU-T-1) derived from a rat nephroblastoma. Virch. Archiv B Cell Pathol., 57: 383-392, 19899. 押村光雄:染色体移入による造腫瘍性抑制に働く染色体の同定 環境変異原研究 11: 35-40, 198910. Shimizu M., Yokota J., Mori N., Shuin T., Shinoda M., Terada M., Oshimura M.: Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR. Oncogene, 5: 185-194, 199011. Oshimura M., Kugoh H., Koi M., Shimizu M., Yamada H., Satoh H., Barrett, J.C.: Transfer of a normal human chromosome 11 suppresses tumorigenicity of some but not all tumor cell lines. J. Cell. Biochem., 42: 135-142, 199012. Oshimura M., Kugoh M.H., Shimizu M., Yamada H., Hashiba H., Horikawa I., Sasaki M.: Multiple chromosomes carrying tumor suppressor activity, via microcell-mediated chromosome transfer, for various tumor cell lines. Genetic Basis for Carcinogenesis: Tumor Suppressor Genes and Oncogenes, Jpn. Sci. Soc. Press., Tokyo/Taylor & Francis, Ltd., London, (eds. Kunudson, A.G.Jr., et al.), pp. 249-257, 199013. Yamada H., Wake N., Fujimoto S., Barrett J.C., Oshimura M.: Multiple chromosomes carrying tumor suppressor activity for a uterine endometrial carcinoma cell line identified by microcell-mediated chromosome transfer. Oncogene, 5: 1141-1147, 199014. Kugoh M.H., Hashiba H., Shimizu M., Oshimura M.: Suggestive evidence for functionally distinct, tumor-suppressor genes on chromosomes 1 and 11 for a human fibrosarcoma cell line, HT1080. Oncogene, 5: 1637-1644, 199015. Yamada H., Horikawa I., Hashiba H., Oshimura M.: Normal human chromosome 1 carries suppressor activity for various phenotypes of a Kirsten murine sarcoma virus-transformed NIH/3T3 cell line. Jpn. J. Cancer Res., 81: 1095-1100, 199016. 佐々木雅弘,押村光雄:染色体移入による癌形質の抑制 実験医学 8: 833-836, 199017. 押村光雄,清水素行:微小核細胞融合法を用いた癌抑制遺伝子の研究 日本臨床 48: 1856-1862, 1990152

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