論文

  1. Murata A, Hayashi SI. CD4+-resident memory T cells mediate long-term local skin immune memory of contact hypersensitivity in BALB/c mice. Front Immunol, in press.
  2. Takaya A, Yamamoto T, Tokoyoda K. Humoral Immunity vs. Salmonella. Front Immunol 10:3155, 2020.
  3. Sarkander J, Hojyo S, Mursell M, Yamasaki Y, Wu TY, Tumes DJ, Miyauchi K, Tran CL, Zhu J, Löhning M, Hutloff A, Mashreghi MF, Kubo M, Radbruch A, Tokoyoda K. Enhanced cell division is required for the generation of memory CD4 T cells to migrate into their proper location. Front Immunol 10:3113, 2020.
  4. Männe C, Takaya A, Yamasaki Y, Mursell M, Hojyo S, Wu TY, Sarkander J, McGrath MA, Cornelis R, Hahne S, Cheng Q, Kawamoto T, Hiepe F, Kaufmann SHE, Yamamoto T, Radbruch A, Tokoyoda K. Salmonella SiiE prevents an efficient humoral immune memory by interfering with IgG+ plasma cell persistence in the bone marrow. Proc Natl Acad Sci USA 116:7425-7430, 2019.
  5. Murata A, Hikosaka M, Yoshino M, Zhou L, Hayashi SI. Kit-independent mast cell adhesion mediated by Notch. Int Immunol 31:69-79, 2019.
  6. Sarkander J, Hojyo S, Tokoyoda K. Vaccination to gain humoral immune memory. Clin Transl Immunol 5:e120, 2016.
  7. Hayashizaki K#, Kimura MY#, Tokoyoda K# (#equally contributed), Hosokawa H, Shinoda K, Hirahara K, Ichikawa T, Onodera A, Hanazawa A, Iwamura C, Kakuta J, Muramoto K, Motohashi S, Tumes DJ, Iinuma T, Yamamoto H, Ikehara Y, Okamoto Y, Nakayama T. Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammaion. Sci Immunol 1:eaaf9154, 2016.
  8. Murata A, Hayashi SI. Notch-mediated cell adhesion. Biology (Basel) 5:5, 2016.
  9. Hojyo S, Sarkander J, Männe C, Mursell M, Hanazawa A, Zimmel D, Zhu J, Paul WE, Fillatreau S, Löhning M, Radbruch A, Tokoyoda K. B cells negatively regulate the establishment of CD49b+T-bet+ resting memory T helper cells in the bone marrow. Front Immunol 7:26, 2016.
  10. Murata A, Yoshino M, Hikosaka M, Okuyama K, Zhou L, Sakano S, Yagita H, Hayashi SI. An evolutionary-conserved function of mammalian Notch family members as cell adhesion molecules. PLoS One 9:e108535, 2014.
  11. Hanazawa A, Löhning M, Radbruch A, Tokoyoda K. CD49b/CD69-dependent generation of resting T helper cell memory. Front Immunol 4:183, 2013.
  12. Hanazawa A, Hayashizaki K, Shinoda K, Yagita H, Okumura K, Löhning M, Hara T, Tani-ichi S, Ikuta K, Eckes B, Radbruch A, Tokoyoda K#, Nakayama T# (#equally contributed). CD49b-dependent establishment of T helper cell memory. Immunol Cell Biol 91:524-531, 2013.
  13. Tokoyoda K, Radbruch A. Signals controlling rest and reactivation of T helper memory lymphocytes in bone marrow. Cell Mol Life Sci 69:1609-1613, 2012.
  14. Shinoda K#, Tokoyoda K# (#equally contributed), Hanazawa A, Hayashizaki K, Zehentmeier S, Hosokawa H, Iwamura C, Koseki H, Tumes DJ, Radbruch A and Nakayama T. Type II membrane protein CD69 regulates the formation of resting T helper memory. Proc Natl Acad Sci USA 109:7409-7414, 2012.
  15. Hayashi SI, Murata A, Okuyama K, Shimoda Y, Hikosaka M, Yasuda H, Yoshino M. Stochastic differentiation into an osteoclast lineage from cloned macrophage-like cells. Biochem Biophys Res Commun 428:303-308, 2012.
  16. Yoshino M, Okuyama K, Murata A, Tomura M, Hayashi SI. CCR7-independent transport of skin antigens occurs in the dermis. Eur J Immunol 42:1459-1467, 2012.
  17. Tokoyoda K, Hauser AE, Nakayama T and Radbruch A. Organization of immunological memory by stroma. Nat Rev Immunol 10:193-200, 2010.
  18. Murata A, Okuyama K, Sakano S, Kajiki M, Hirata T, Yagita H, Zúñiga-Pflücker JC, Miyake K, Akashi-Takamura S, Moriwaki S, Niida S, Yoshino M, Hayashi S. A Notch ligand, Delta-like 1 functions as an adhesion molecule for mast cells. J Immunol 185:3905-3912, 2010.
  19. Tokoyoda K, Zehentmeier S and Radbruch A. Organization and maintenance of immunological memory by stroma niches. Eur J Immunol 39:2095-2099, 2009.
  20. Tokoyoda K, Zehentmeier S, Hegazy AN, Albrecht I, Grün JR, Löhning M and Radbruch A. Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow. Immunity 30:721-730, 2009.
  21. Yoshino M, Yamazaki H, Hayashi S. Analysis of capturing skin antigens in the steady state using milk fat globule EGF factor 8-deficient skin-hyperpigmented mice. Immunol Lett 115:131-137, 2008.
  22. Yoshino M, Yamazaki H, Shultz LD, Hayashi Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes. Int Immunol 18:1541-1548, 2006.
  23. Tokoyoda K, Egawa T, Sugiyama T, Choi BI and Nagasawa T. Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity 20:707-718, 2004.
  24. Tokoyoda K, Tsujikawa K, Matsushita H, Ono Y, Hayashi T, Harada Y, Abe R, Kubo M and Yamamoto H. Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells. Int Immunol 16:643-653, 2004.
  25. Yoshino M, Yamazaki H, Nakano H, Kakiuchi T, Ryoke K, Kunisada T, Hayashi S. Distinct antigen trafficking from skin in the steady and active states. Int Immunol 15:773-779, 2003.
  26. Yoshino M, Yamazaki H, Yoshida H, Niida S, Nishikawa S, Ryoke K, Kunisada T, Hayashi S. Reduction of osteoclasts in a critical embryonic period is essential for inhibition of mouse tooth eruption. J Bone Miner Res 18:108-116, 2003.
  27. Tokoyoda K, Takemoto Y, Nakayama T, Arai T and Kubo M. Synergism between the calmodulin-binding and autoinhibitory domains on calcineurin is essential for the induction of their phosphatase activity. J Biol Chem 275:11728-11734, 2000.