鳥取大学における染色体医工学研究の歩み
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Wakayama T., Oshimura M.: Enhanced apoptosis during early neuronal diff erentiation in mouse ES cells with autosomal imbalance. Cell Res., 19:247-58, 20086. Kinoshita Y, Kamitani H, Mamun MH, Wasita B, Kazuki Y, Hiratsuka M, Oshimura M, Watanabe T.: A gene delivery system with a human artifi cial chromosome vector based on migration of mesenchymal stem cells towards human glioblastoma HTB14 cells. Neurol Res. 32:429-37, 20097. Takahashi Y, Tsuji S, Kazuki Y, Noguchi M, Arifuku I, Umebayashi Y, Nakanishi T, Oshimura M, Sato K.: Development of evaluation system for bioactive substances using human artifi cial chromosome-mediated osteocalcin gene expression. J Biochem. 148:29-34,20108. Wang CC, Kazuki Y, Oshimura M, Ikeo K, Gojobori T.: Gene dosage ibalance of human chromosome 21 in mouse embryonic stem cells diff erentiating to neurons. Gene. 481:93-101, 20119. Nawata H., Kashino G., Tano K., Daino K., Shimada Y., Kugoh H., Oshimura M., Watanabe M.: Dysregulation of gene expression in the artifi cial human trisomy cells of chromosome 8 associated with transformed cell phenotypes. Plos One. 6:e25319, 2011168

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