鳥取大学における染色体医工学研究の歩み

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7. Yamada H., Kunisato A., Kawahara M., Tahimic C.G., Ren X., Ueda H., Nagamune T., Katoh M., Inoue T., Nishikawa M., Oshimura M.: Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artifi cial chromosome. J Hum Genet., 51:147-50, 2006 8. Suda T., Katoh M., Hiratsuka M., Takiguchi M., Kazuki Y., Inoue T., Oshimura M.: Heat-regulated production and secretion of insulin from a human artifi cial chromosome vector. Biochem Biophys Res Commun., 340:1053-61, 2006 9. 香月康宏,押村光雄:ヒト人工染色体ベクター導入と遺伝子・再生医療への可能性 分子呼吸器病 Vol.10 No.4 34(316)-66(318) 200610. 任 鮮英,押村光雄:遺伝子導入のためのヒト人工染色体ベクタ分子細胞治療 Vol.5 No.3 39(237)-46(244) 200611. 平塚正治,押村光雄:再生医療 11 Vol.5 No.4, 72-77, 200612. Yamaguchi S., Ren X., Katoh M., Miyata K., Fukushima H., Inoue T., Oshimura M.: A new method of microcell-mediated transfer of human Artifi cial chromosomes using a hemagglutinating virus of Japan envelope. Chromosome Science, 65-73, 200613. Oshimura M., Katoh M.: Transfer human artifi cial chromosome vectors into stem cells. Reproductive BioMedicine Online. Vol.16 No.1, 57-69, 200814. Kazuki Y., Hoshiya H., Kai Y., Abe S., Takiguchi M., Osaki M.,Kawazoe S., Katoh M., Kanatsu-Shinohara M., Inoue K., Kajitani N., Yoshino N., Shirayoshi Y., Ogura A., Shinohara T., Barrett J.C., Oshimura M.: Correction of a genetic defect in multipotent Germline stem cells using a human artifi cial chromosome. Gene Therapy, 15:617-24, 200815. Shitara S., Kakeda M., Nagata K., Hiratsuka M., Sano A., Osawa K., Okazaki A., Katoh M., Kazuki Y., Oshimura M.: Telomerase-mediated life-span extension of human primary fi broblasts by human artifi cial chromosome(HAC) vector. BBRC., 369:807-11, 200816. Yamada H., Li Yanze C., Nishikawa M., Oshimura M., Inoue T.,: Introduction of a CD40L genomic fragment via a human artificial chromosome vector permits cell type-specific gene expression and induces immunoglobulin secretion. J Hum Genet., 53:447-53, 200817. 香月康宏,松岡隆之,押村光雄:ヒト人工染色体を用いたiPS細胞の作製と遺伝子再生医療へ向けて. 再生医療 Vol. 7 No. 3, 200818. Hoshiya H., Kazuki Y., Abe S., Takiguchi M., Kajitani N., Watanabe Y., Yoshino T., Shirayoshi Y., Higaki K., Messina G., Cossu G., Oshimura M.,: A highly stable and non-integrated human artifi cial chromosome(HAC) containing the 2.4Mb entire human dystrophin gene.Mol Therapy, 17:309-317, 200919. Kazuki Y., Hiratsuka M., Takiguchi M., Osaki M., Kajitani N., Hoshiya H., Hiramatsu K., Yoshino T., Kazuki K., Ishihara C., Takehara S., Higaki K., Nakagawa M., Takahashi K., Yamanaka S., Oshimura M.: Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther. 386-393,201020. Katoh M., Kazuki Y., Kazuki K., Kajitani N., Takiguchi M., Nakayama Y., Nakamura T., Oshimura M.: Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell- mediated chromosome transfer. BMC Biotechnol. 10:37,201021. Kurosaki H., Hiratsuka M., Imaoka N., Iida Y., Uno N., Kazuki Y., Ishihara C., Yakura Y., Mimuro J., Sakata Y., Takeya H., Oshimura M.: Integration-free and stable expression of FVIII using a human artifi cial chromosome. Journal of Human Genetics. 56:727-733, 201122. Tedesco F.S., Hoshiya H., DʼAntona G., Gerli M. F.M., Messina G., Antonini S., Tonlorenzi R., Benedetti S., Berghella L., Torrente Y., Kazuki H., Bottinelli R., Oshimura M., Cossu G.: Stem Cell-Mediated transfer of a Human Artificial Chromosome Containing the Entire Dystrophin Locus Ameliorates Muscular Dystrophy. Science Transl Med. 3:96ra78, 201123. 香月康宏,押村光雄:iPS細胞とヒト人工染色体ベクターを用いた新たな筋ジストロフィー遺伝子治療に向けて, Medical Science Digest, 201124. 香月康宏,押村光雄:ヒト人工染色体ベクターによる遺伝子細胞治療へ向けて, 日本臨床 2011 p69.160

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