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准教授 久郷 裕之

鳥取大学大学院医学系研究科
機能再生医科学専攻
生体機能医工学講座
遺伝子機能工学部門
北里大学卒業 、神奈川県立がんセンター臨床研究所 、鳥取大学医学部生命科
学科細胞工学助手、M.D. Andersonがんセンター 研究員、 鳥取大学大学院医
学系研究科機能再生医科学専攻生体機能工学講座遺伝子機能工学部門准教授

業績

Kleymenova E., Ibraghimov-Beskrovnaya O., Kugoh H., Everitt J., Xu H., Kiguchi K., Landes G.,Harris P. and Walker C.: Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene Mol Cell 7(4):823-832, 2001

Kugoh H
., Kleymenova E., and Walker C. Retention of membrane-localized -catenin in cells lacking functional polycystin-1 and tuberin. Molecular Carcinogenesis 33 (3): 131-136, 2002
Kugoh H, Nakamoto H, Inoue J, Funaki K, Barrett JC, Oshimura M. Multiple human chromosomes carrying tumor-suppressor functions for the mouse melanoma cell line B16-F10, identified by microcell-mediated chromosome transfer. Molecular Carcinogenesis 35(3): 148-156, 2002
Kugoh H, Shigenami K, Funaki K, Barrett JC, Oshimura M. Human chromosome 5 carries a putative telomerase repressor gene. Genes Chromosomes Cancer 36(1):37-47, 2003Yawata T, Kamino H, Kugoh H, Katoh M, Nomura N, Oishi M, Horikawa I, Barrett JC, Oshimura M. Identification of a 600-kb region on human chromosome 1q42.3 inducing cellular senescence. Oncogene 22 (2): 281-290, 2003Niemitz EL, DeBaun MR, Fallon J, Murakami K, Kugoh H, Oshimura M, Feinberg AP. Microdeletion of LIT1 in Familial Beckwith-Wiedemann Syndrome. Am J Hum Genet. 75(5): 844-849, 2004.Nakano S, Murakami K, Meguro M, Soejima H, Higashimoto K, Urano T, Kugoh H, Mukai T, Ikeguchi M, Oshimura M.Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KvDMR1 in colorectal cancers. Cancer Sci. 97(11), 1147-1154, 2006

久郷裕之、中野星児、押村光雄 染色体の構造と機能 ゲノムワイドに展開するエピジェネティクス医科学:111-118, 羊土社, 2006


Murakami, K., Oshimura, M., Kugoh, H. Suggestive evidence for chromosomal localization of non-coding RNA from imprinted LIT1. J. Human Genetics, 52(11): 926-933,2007
久郷裕之、押村光雄 染色体の構造と機能 エピジェネティクスと臨床検査 52(6)605-612, 臨床検査(医学書院)2008

Murakami, K., Ohhira, T., Oshiro, E., Qi, D., Oshimura, M., Kugoh, H. Identification of the chromatin regions coated by non-coding Xist RNA. Cytogenetic and Genome Research, 125(1):19-25, 2009

Qi DL, Ohhira T, Oshimura M, Kugoh H. Human chromosome 5 carries a transcriptional regulator of human telomerase reverse transcriptase (hTERT). Biochem Biophys Res Commun. 2010 Aug 6;398(4):695-701. Epub 2010 Jul 16

Abe S, Tanaka H, Notsu T, Horike S, Fujisaki C, Qi DL, Ohhira T, Gilley D, Oshimura M, Kugoh H. Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.Genome Integr. 2010 May 26;1(1):6.

Qi DL, Ohhira T, Fujisaki C, Inoue T, Ohta T, Osaki M, Ohshiro E, Seko T, Aoki S, Oshimura M, Kugoh H. Identification of PITX1 as a TERT suppressor gene located on human chromosome 5. Mol Cell Biol. 2011 Apr;31(8):1624-36. Epub 2011 Feb 7.

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Department of Biomedical Science, Division of Molecular Genetics and Biofunction.
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